Urinary excretion of pyridoxine and 4‐pyridoxic acid in rheumatoid arthritis

Anne B. McKusick; Roger W. Sherwin; Lynn Grupenhoff Jones; Jeng M. Hsu

doi:10.1002/art.1780070604

Urinary excretion of pyridoxine and 4‐pyridoxic acid in rheumatoid arthritis

Anne B. McKusick, Roger W. Sherwin, Lynn Grupenhoff Jones, Jeng M. Hsu

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Seven patients with active rheumatoid arthritis excreted significantly less pyridoxine in the urine than controls when patient‐control pairs were fed identical constant diets while receiving no drugs. After a 10 mg. dose of pyridoxine hydrochloride, change in objectively measured stiffness appeared to be inversely related to change in urinary excretion of pyridoxine. The study does not necessarily show that giving rheumatoid arthritics pyridoxine is beneficial.

Original language	English (US)
Pages (from-to)	636-653
Number of pages	18
Journal	Arthritis & Rheumatism
Volume	7
Issue number	6
DOIs	https://doi.org/10.1002/art.1780070604
State	Published - Dec 1964
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Rheumatology
Immunology
Pharmacology (medical)

Access to Document

10.1002/art.1780070604

Cite this

@article{de63f2453ee941ab9fe5cd89a97e26eb,

title = "Urinary excretion of pyridoxine and 4‐pyridoxic acid in rheumatoid arthritis",

abstract = "Seven patients with active rheumatoid arthritis excreted significantly less pyridoxine in the urine than controls when patient‐control pairs were fed identical constant diets while receiving no drugs. After a 10 mg. dose of pyridoxine hydrochloride, change in objectively measured stiffness appeared to be inversely related to change in urinary excretion of pyridoxine. The study does not necessarily show that giving rheumatoid arthritics pyridoxine is beneficial.",

author = "McKusick, {Anne B.} and Sherwin, {Roger W.} and Jones, {Lynn Grupenhoff} and Hsu, {Jeng M.}",

year = "1964",

month = dec,

doi = "10.1002/art.1780070604",

language = "English (US)",

volume = "7",

pages = "636--653",

journal = "Arthritis & Rheumatism",

issn = "0004-3591",

publisher = "John Wiley and Sons Ltd",

number = "6",

}

TY - JOUR

T1 - Urinary excretion of pyridoxine and 4‐pyridoxic acid in rheumatoid arthritis

AU - McKusick, Anne B.

AU - Sherwin, Roger W.

AU - Jones, Lynn Grupenhoff

AU - Hsu, Jeng M.

PY - 1964/12

Y1 - 1964/12

N2 - Seven patients with active rheumatoid arthritis excreted significantly less pyridoxine in the urine than controls when patient‐control pairs were fed identical constant diets while receiving no drugs. After a 10 mg. dose of pyridoxine hydrochloride, change in objectively measured stiffness appeared to be inversely related to change in urinary excretion of pyridoxine. The study does not necessarily show that giving rheumatoid arthritics pyridoxine is beneficial.

AB - Seven patients with active rheumatoid arthritis excreted significantly less pyridoxine in the urine than controls when patient‐control pairs were fed identical constant diets while receiving no drugs. After a 10 mg. dose of pyridoxine hydrochloride, change in objectively measured stiffness appeared to be inversely related to change in urinary excretion of pyridoxine. The study does not necessarily show that giving rheumatoid arthritics pyridoxine is beneficial.

UR - http://www.scopus.com/inward/record.url?scp=0001533139&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0001533139&partnerID=8YFLogxK

U2 - 10.1002/art.1780070604

DO - 10.1002/art.1780070604

M3 - Article

C2 - 14240622

AN - SCOPUS:0001533139

SN - 0004-3591

VL - 7

SP - 636

EP - 653

JO - Arthritis & Rheumatism

JF - Arthritis & Rheumatism

IS - 6

ER -

Urinary excretion of pyridoxine and 4‐pyridoxic acid in rheumatoid arthritis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this