TY - JOUR
T1 - Urea small molecule agonists on mouse melanocortin receptors
AU - Joseph, Christine G.
AU - Bauzo, Rayna M.
AU - Xiang, Zhimin
AU - Haskell-Luevano, Carrie
N1 - Funding Information:
This work has been supported by NIH Grant RO1-DK57080. Carrie Haskell-Luevano is a recipient of a Burroughs Wellcome Fund Career Award in the Biomedical Sciences. Special thanks to Jim Rocca, McKnight Brain Institute, University of Florida for help with NMR spectroscopy.
PY - 2003/6/16
Y1 - 2003/6/16
N2 - A series of urea compounds based on the tripeptide Phe-Trp-Lys were synthesized and pharmacologically characterized at the mouse melanocortin receptors. The results include identification of novel melanocortin receptor agonists with potencies ranging from nanomolar to micromolar.
AB - A series of urea compounds based on the tripeptide Phe-Trp-Lys were synthesized and pharmacologically characterized at the mouse melanocortin receptors. The results include identification of novel melanocortin receptor agonists with potencies ranging from nanomolar to micromolar.
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U2 - 10.1016/S0960-894X(03)00318-4
DO - 10.1016/S0960-894X(03)00318-4
M3 - Article
C2 - 12781199
AN - SCOPUS:0038440569
SN - 0960-894X
VL - 13
SP - 2079
EP - 2082
JO - Bioorganic and Medicinal Chemistry Letters
JF - Bioorganic and Medicinal Chemistry Letters
IS - 12
ER -