Urea small molecule agonists on mouse melanocortin receptors

Christine G. Joseph, Rayna M. Bauzo, Zhimin Xiang, Carrie Haskell-Luevano

Research output: Contribution to journalArticle

Abstract

A series of urea compounds based on the tripeptide Phe-Trp-Lys were synthesized and pharmacologically characterized at the mouse melanocortin receptors. The results include identification of novel melanocortin receptor agonists with potencies ranging from nanomolar to micromolar.

Original languageEnglish (US)
Pages (from-to)2079-2082
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume13
Issue number12
DOIs
StatePublished - Jun 16 2003

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ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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