Upper gastrointestinal bleeding from metastatic testicular cancer

Adeyinka O. Laiyemo, Momodu Jack, Fitzroy W. Dawkins, Duane T. Smoot

Research output: Contribution to journalArticlepeer-review

Abstract

We report a 22-year-old man who presented with a 2-week history of intermittent melena and worsening scrotal and leg swelling. His medical history was significant for testicular cancer for which he had undergone orchiectomy, lymphadenectomy, and platinum-based chemotherapy. Esophagogastroduodenoscopy (EGD) performed revealed polypoid mass lesions in the second and third portions of the duodenum. Biopsy revealed mixed germ cell tumor with immature teratoma, the same histology as his testicular cancer. His chemotherapy was changed to an ifosphamide-based regimen and a repeat upper endoscopic examination 5 months later revealed complete resolution of previously noted polypoid duodenal mass lesions. This also demonstrates the effectiveness of ifosphamide as second-line therapy in the setting of resistance to platinum-based therapy.

Original languageEnglish (US)
Pages (from-to)808-809
Number of pages2
JournalJournal of the National Medical Association
Volume101
Issue number8
DOIs
StatePublished - Aug 2009

Keywords

  • Cancer
  • Chemotherapy
  • Intestines
  • Men's health
  • Metastasis

ASJC Scopus subject areas

  • Medicine(all)

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