Upper airway pressure-flow relationships in obstructive sleep apnea

Philip L Smith, Robert A Wise, A. R. Gold, Alan R Schwartz, S. Permutt

Research output: Contribution to journalArticle

Abstract

We examined the pressure-flow relationships in patients with obstructive sleep apnea utilizing the concepts of a Starling resistor. In six patients with obstructive sleep apnea, we applied incremental levels of positive pressure through a nasal mask during non-rapid-eye-movement sleep. A positive critical opening pressure (Pcrit) of 3.3±3.3 (SD) cmH2O was demonstrated. As nasal pressure was raised above Pcrit, inspiratory airflow increased in proportion to the level of positive pressure applied until apneas were abolished (P

Original languageEnglish (US)
Pages (from-to)789-795
Number of pages7
JournalJournal of Applied Physiology
Volume64
Issue number2
StatePublished - 1988

Fingerprint

Obstructive Sleep Apnea
Pressure
Nose
Starlings
Apnea
Eye Movements
Masks
Sleep

ASJC Scopus subject areas

  • Endocrinology
  • Physiology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Upper airway pressure-flow relationships in obstructive sleep apnea. / Smith, Philip L; Wise, Robert A; Gold, A. R.; Schwartz, Alan R; Permutt, S.

In: Journal of Applied Physiology, Vol. 64, No. 2, 1988, p. 789-795.

Research output: Contribution to journalArticle

Smith, PL, Wise, RA, Gold, AR, Schwartz, AR & Permutt, S 1988, 'Upper airway pressure-flow relationships in obstructive sleep apnea', Journal of Applied Physiology, vol. 64, no. 2, pp. 789-795.
Smith, Philip L ; Wise, Robert A ; Gold, A. R. ; Schwartz, Alan R ; Permutt, S. / Upper airway pressure-flow relationships in obstructive sleep apnea. In: Journal of Applied Physiology. 1988 ; Vol. 64, No. 2. pp. 789-795.
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