Update on Sjögren Syndrome and Other Causes of Sicca in Older Adults

Abstract

Dry eye and dry mouth symptoms are each reported by up to 30% of persons more than 65 years of age, particularly in women. Medication side effects are the most common contributing factors. The evaluation of these symptoms requires measures of ocular and oral dryness. Sjögren syndrome is the prototypical disease associated with dryness of the eyes and mouth and predominantly affects women in their perimenopausal and postmenopausal years. In addition to topical treatment of the mucosal dryness, patients with Sjögren syndrome may require treatment with systemic immunomodulatory and immunosuppressive agents to manage a variety of extraglandular manifestations.

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Keywords

  • Aging
  • Dry eye
  • Salivary hypofunction
  • Sjögren syndrome
  • Xerostomia

ASJC Scopus subject areas

  • Rheumatology

Cite this

Update on Sjögren Syndrome and Other Causes of Sicca in Older Adults. / Baer, Alan; Walitt, Brian.

In: Rheumatic Disease Clinics of North America, Vol. 44, No. 3, 01.08.2018, p. 419-436.

Research output: Contribution to journalReview article