Update on role of chemotherapy in head and neck squamous cell cancer

Research output: Contribution to journalArticle

Abstract

Head and neck squamous cell cancer (HNSCC) is most commonly a tobacco-related disease, affecting nearly 600,000 people worldwide each year. For decades, HNSCC has been treated successfully with multimodality treatments including, surgery, radiation, and chemotherapy, though the 'perfect' treatment paradigm remains elusive. This review will discuss a number of clinical trials, comparing various combinations of chemotherapy and the settings in which they are most successful. Promising research and recent data on the combination of cytotoxic chemotherapy with new biological agents indicate chemotherapy plays a critical role in treatment of HNSCC and will only continue to improve.

Original languageEnglish (US)
Pages (from-to)85-95
Number of pages11
JournalIndian Journal of Surgical Oncology
Volume1
Issue number2
DOIs
StatePublished - Apr 2010

Fingerprint

Squamous Cell Neoplasms
Head and Neck Neoplasms
Head
Combination Drug Therapy
Drug Therapy
Biological Factors
Tobacco
Therapeutics
Clinical Trials
Radiation
Research

Keywords

  • cetuximab
  • chemoradiation
  • chemotherapy
  • Head and neck cancer
  • induction chemotherapy
  • targeted therapy

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Update on role of chemotherapy in head and neck squamous cell cancer. / Marur, S.; Forastiere, Arlene A.

In: Indian Journal of Surgical Oncology, Vol. 1, No. 2, 04.2010, p. 85-95.

Research output: Contribution to journalArticle

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