Abstract
The incidence and prevalence of systemic hypertension are reaching global epidemic proportions. Despite a diverse pharmacologic armamentarium of agents to treat high blood pressure, suboptimal control remains a significant problem in as many as 43% of patients and this rate has not significantly improved over the past 2 decades. There are a variety of factors contributing to this including patient nonadherence due to complex drug regimens and medication side effects, undertreatment, and treatment resistance. There, thus, remains a need to develop novel agents and approaches to antihypertensive therapy that facilitate attainment of optimal blood pressure levels. This monograph will review a number of new pharmacologic targets and interventions as well as a novel method of drug delivery to patients.
Original language | English (US) |
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Pages (from-to) | 257-267 |
Number of pages | 11 |
Journal | Journal of Cardiovascular Pharmacology and Therapeutics |
Volume | 15 |
Issue number | 3 |
DOIs | |
State | Published - Sep 2010 |
Keywords
- antihypertensives
- drug effects
- hypertension
- renin-angiotensin system
ASJC Scopus subject areas
- Pharmacology
- Cardiology and Cardiovascular Medicine
- Pharmacology (medical)