Update in management of ganciclovir-resistant cytomegalovirus infection

Research output: Contribution to journalReview articlepeer-review

Abstract

Antiviral-resistant cytomegalovirus infection remains a feared complication of transplantation but is less frequently seen in AIDS patients in the current era. New research on resistance mutations and pathogenesis has enhanced clinical understanding of risk. Although preemptive strategies and valganciclovir prophylaxis are associated with less resistance than oral ganciclovir, resistant cytomegalovirus infection has not been eliminated. Several strategies and newer drugs hold promise for the future.

Original languageEnglish (US)
Pages (from-to)433-437
Number of pages5
JournalCurrent opinion in infectious diseases
Volume21
Issue number4
DOIs
StatePublished - Aug 1 2008
Externally publishedYes

Keywords

  • Antiviral resistance
  • Cytomegalovirus
  • Ganciclovir
  • Transplantation

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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