Abstract
Antiviral-resistant cytomegalovirus infection remains a feared complication of transplantation but is less frequently seen in AIDS patients in the current era. New research on resistance mutations and pathogenesis has enhanced clinical understanding of risk. Although preemptive strategies and valganciclovir prophylaxis are associated with less resistance than oral ganciclovir, resistant cytomegalovirus infection has not been eliminated. Several strategies and newer drugs hold promise for the future.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 433-437 |
| Number of pages | 5 |
| Journal | Current opinion in infectious diseases |
| Volume | 21 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 2008 |
| Externally published | Yes |
Keywords
- Antiviral resistance
- Cytomegalovirus
- Ganciclovir
- Transplantation
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases