Unusual sites of extraskeletal metastases of ewing sarcoma after allogeneic hematopoietic stem cell transplantation

Christian M. Capitini; Joanne Derdak; Marybeth S. Hughes; Cynthia P. Love; Kristin Baird; Crystal L. MacKall; Terry J. Fry

doi:10.1097/MPH.0b013e31819146e5

Unusual sites of extraskeletal metastases of ewing sarcoma after allogeneic hematopoietic stem cell transplantation

Christian M. Capitini, Joanne Derdak, Marybeth S. Hughes, Cynthia P. Love, Kristin Baird, Crystal L. MacKall, Terry J. Fry

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Allogeneic stem cell transplantation (SCT) for solid tumors remains under investigation. We report a case of extended disease stability after a nonmyeloablative peripheral blood SCT for metastatic, refractory Ewing sarcoma. Of note, the patient developed metastatic disease to 2 unusual sites-the brain and small intestine. The allogeneic SCT environment may alter typical metastatic patterns, and may represent an ideal platform to manipulate and enhance the antitumor immune response. Further clinical trials are needed to evaluate the role for allogeneic SCT for this disease.

Original language	English (US)
Pages (from-to)	142-144
Number of pages	3
Journal	Journal of Pediatric Hematology/Oncology
Volume	31
Issue number	2
DOIs	https://doi.org/10.1097/MPH.0b013e31819146e5
State	Published - Feb 2009
Externally published	Yes

Keywords

Allogeneic stem cell transplant
Ewing sarcoma
Metastasis

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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10.1097/MPH.0b013e31819146e5

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title = "Unusual sites of extraskeletal metastases of ewing sarcoma after allogeneic hematopoietic stem cell transplantation",

abstract = "Allogeneic stem cell transplantation (SCT) for solid tumors remains under investigation. We report a case of extended disease stability after a nonmyeloablative peripheral blood SCT for metastatic, refractory Ewing sarcoma. Of note, the patient developed metastatic disease to 2 unusual sites-the brain and small intestine. The allogeneic SCT environment may alter typical metastatic patterns, and may represent an ideal platform to manipulate and enhance the antitumor immune response. Further clinical trials are needed to evaluate the role for allogeneic SCT for this disease.",

keywords = "Allogeneic stem cell transplant, Ewing sarcoma, Metastasis",

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T1 - Unusual sites of extraskeletal metastases of ewing sarcoma after allogeneic hematopoietic stem cell transplantation

AU - Capitini, Christian M.

AU - Derdak, Joanne

AU - Hughes, Marybeth S.

AU - Love, Cynthia P.

AU - Baird, Kristin

AU - MacKall, Crystal L.

AU - Fry, Terry J.

PY - 2009/2

Y1 - 2009/2

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AB - Allogeneic stem cell transplantation (SCT) for solid tumors remains under investigation. We report a case of extended disease stability after a nonmyeloablative peripheral blood SCT for metastatic, refractory Ewing sarcoma. Of note, the patient developed metastatic disease to 2 unusual sites-the brain and small intestine. The allogeneic SCT environment may alter typical metastatic patterns, and may represent an ideal platform to manipulate and enhance the antitumor immune response. Further clinical trials are needed to evaluate the role for allogeneic SCT for this disease.

KW - Allogeneic stem cell transplant

KW - Ewing sarcoma

KW - Metastasis

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Unusual sites of extraskeletal metastases of ewing sarcoma after allogeneic hematopoietic stem cell transplantation

Abstract

Keywords

ASJC Scopus subject areas

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