Unusual sites of extraskeletal metastases of ewing sarcoma after allogeneic hematopoietic stem cell transplantation

Christian M. Capitini, Joanne Derdak, Marybeth S. Hughes, Cynthia P. Love, Kristin Baird, Crystal L. MacKall, Terry J. Fry

Research output: Contribution to journalArticlepeer-review

Abstract

Allogeneic stem cell transplantation (SCT) for solid tumors remains under investigation. We report a case of extended disease stability after a nonmyeloablative peripheral blood SCT for metastatic, refractory Ewing sarcoma. Of note, the patient developed metastatic disease to 2 unusual sites-the brain and small intestine. The allogeneic SCT environment may alter typical metastatic patterns, and may represent an ideal platform to manipulate and enhance the antitumor immune response. Further clinical trials are needed to evaluate the role for allogeneic SCT for this disease.

Original languageEnglish (US)
Pages (from-to)142-144
Number of pages3
JournalJournal of Pediatric Hematology/Oncology
Volume31
Issue number2
DOIs
StatePublished - Feb 2009

Keywords

  • Allogeneic stem cell transplant
  • Ewing sarcoma
  • Metastasis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

Fingerprint

Dive into the research topics of 'Unusual sites of extraskeletal metastases of ewing sarcoma after allogeneic hematopoietic stem cell transplantation'. Together they form a unique fingerprint.

Cite this