Unusual insertion and deletion at codon 67 and 69 of HIV type 1 subtype C reverse transcriptase among first-line highly active antiretroviral treatment-failing south Indian patients: Association with other resistance mutations

Shanmugam Saravanan, Vidya Madhavan, Rami Kantor, Sathasivam Sivamalar, Selvamurthi Gomathi, Sunil S. Solomon, Nagalingeswaran Kumarasamy, Davey M. Smith, Robert T. Schooley, Suniti Solomon, Pachamuthu Balakrishnan

Research output: Contribution to journalArticle

Abstract

We report a high frequency of drug resistance mutations among patients with unusual insertions or deletions at the β34 hairpin-loop-coding region of HIV-1 subtype C reverse transcriptase, during failure of first-line antiretroviral therapy containing only reverse transcriptase inhibitors in Chennai, India.

Original languageEnglish (US)
Pages (from-to)1763-1765
Number of pages3
JournalAIDS research and human retroviruses
Volume28
Issue number12
DOIs
StatePublished - Dec 1 2012
Externally publishedYes

ASJC Scopus subject areas

  • Immunology
  • Virology
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Unusual insertion and deletion at codon 67 and 69 of HIV type 1 subtype C reverse transcriptase among first-line highly active antiretroviral treatment-failing south Indian patients: Association with other resistance mutations'. Together they form a unique fingerprint.

  • Cite this