Unrealistic Expectations in the Diagnosis and Treatment of Ovarian Cancer

Jeffrey T. Kirchner, M. A. Friedman, B. A. Chabner, E. L. Trimble, J. Adams, S. G. Arbuck, Daniel J. Morris, Charles S. Eytel, Albert Kerns, Gene Wilder, C. D. Granai

Research output: Contribution to journalLetterpeer-review


To the Editor: Dr. Granai's recent Sounding Board article, “Ovarian Cancer – Unrealistic Expectations” (July 16 issue),1 succinctly highlights the problem of performing excessive screening tests for diseases for which we have no efficacious treatments. The author uses ovarian cancer as an example. A similar argument can be made for prostatic carcinoma, the most common cancer among American men2. Despite the availability of transrectal ultrasonography, testing for prostate-specific antigen (PSA), and newer agents such as flutamide and leuprolide, the age-adjusted mortality for prostatic cancer has not changed since 19492,3. Moreover, neither PSA testing nor transrectal ultrasonography is…

Original languageEnglish (US)
Pages (from-to)663-665
Number of pages3
JournalNew England Journal of Medicine
Issue number9
StatePublished - Mar 4 1993
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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