Abstract
Focal tumor cell PD-L1 expression adjacent to TIL can be used as a surrogate marker of an ongoing antitumor host response, which may be unleashed by PD-1 blockade. Tumor cell PD-L1 expression is superior to TIL PD-1 expression and the presence of TIL alone, when predicting response to anti-PD-1 therapy.
Original language | English (US) |
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Pages (from-to) | e963413-1-e963413-3 |
Journal | OncoImmunology |
Volume | 3 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2 2014 |
Keywords
- PD-1
- PD-L1
- PD-L2
- cancer immunotherapy
- tumor microenvironment
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Oncology