Unique presentations and chronic complications in adult cystic fibrosis: Do they teach us anything about CFTR?

Michael P. Boyle

doi:10.1186/rr23

Unique presentations and chronic complications in adult cystic fibrosis: Do they teach us anything about CFTR?

Michael P. Boyle

Research output: Contribution to journal › Comment/debate › peer-review

2 Scopus citations

Abstract

The increase in numbers of adults with cystic fibrosis (CF) has allowed us to identify previously unrecognized chronic complications of CF, as well as appreciate unique presentations of cystic fibrosis-related diseases. Do these chronic complications and unique presentations provide us with new insight into cystic fibrosis transmembrane conductance regulator (CFTR) function? Current data suggest that the 'chronic complications' reveal mainly the effect of a long-term absence of previously recognized CFTR functions. In contrast, the 'unique presentations' provide new insight into the role of CFTR in different tissues.

Original language	English (US)
Pages (from-to)	133-135
Number of pages	3
Journal	Respiratory research
Volume	1
Issue number	1
DOIs	https://doi.org/10.1186/rr23
State	Published - Nov 16 2000
Externally published	Yes

Keywords

Congenital bilateral absence of the vas deferens
Cystic fibrosis
Cystic fibrosis transmembrane conductance regulator
Malignancy
Pancreatitis

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1186/rr23

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title = "Unique presentations and chronic complications in adult cystic fibrosis: Do they teach us anything about CFTR?",

abstract = "The increase in numbers of adults with cystic fibrosis (CF) has allowed us to identify previously unrecognized chronic complications of CF, as well as appreciate unique presentations of cystic fibrosis-related diseases. Do these chronic complications and unique presentations provide us with new insight into cystic fibrosis transmembrane conductance regulator (CFTR) function? Current data suggest that the 'chronic complications' reveal mainly the effect of a long-term absence of previously recognized CFTR functions. In contrast, the 'unique presentations' provide new insight into the role of CFTR in different tissues.",

keywords = "Congenital bilateral absence of the vas deferens, Cystic fibrosis, Cystic fibrosis transmembrane conductance regulator, Malignancy, Pancreatitis",

author = "Boyle, {Michael P.}",

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year = "2000",

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doi = "10.1186/rr23",

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AU - Boyle, Michael P.

PY - 2000/11/16

Y1 - 2000/11/16

N2 - The increase in numbers of adults with cystic fibrosis (CF) has allowed us to identify previously unrecognized chronic complications of CF, as well as appreciate unique presentations of cystic fibrosis-related diseases. Do these chronic complications and unique presentations provide us with new insight into cystic fibrosis transmembrane conductance regulator (CFTR) function? Current data suggest that the 'chronic complications' reveal mainly the effect of a long-term absence of previously recognized CFTR functions. In contrast, the 'unique presentations' provide new insight into the role of CFTR in different tissues.

AB - The increase in numbers of adults with cystic fibrosis (CF) has allowed us to identify previously unrecognized chronic complications of CF, as well as appreciate unique presentations of cystic fibrosis-related diseases. Do these chronic complications and unique presentations provide us with new insight into cystic fibrosis transmembrane conductance regulator (CFTR) function? Current data suggest that the 'chronic complications' reveal mainly the effect of a long-term absence of previously recognized CFTR functions. In contrast, the 'unique presentations' provide new insight into the role of CFTR in different tissues.

KW - Congenital bilateral absence of the vas deferens

KW - Cystic fibrosis

KW - Cystic fibrosis transmembrane conductance regulator

KW - Malignancy

KW - Pancreatitis

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AN - SCOPUS:0038181738

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JO - Respiratory research

JF - Respiratory research

IS - 1

ER -

Unique presentations and chronic complications in adult cystic fibrosis: Do they teach us anything about CFTR?

Abstract

Keywords

ASJC Scopus subject areas

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