Uninvolved skin from psoriatic patients develops signs of involved psoriatic skin after being grafted onto nude mice

Jorma E. Fraki, Robert A. Briggaman, Gerald S. Lazarus

Research output: Contribution to journalArticle

Abstract

Clinically involved psoriatic epidermis maintains its histological appearance, increased labeling index, and increased level of plasminogen activator after being grafted onto athymic nude mice. Uninvolved psoriatic epidermis develops increases in plasminogen activator activity after being grafted onto athymic nude mice; this is accompanied by an increased labeling index. Thus, psoriatic skin can develop markers of psoriasis independent of the host.

Original languageEnglish (US)
Pages (from-to)685-687
Number of pages3
JournalScience
Volume215
Issue number4533
DOIs
StatePublished - Jan 1 1982
Externally publishedYes

ASJC Scopus subject areas

  • General

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