Unilateral segmental agenesis of the vertebral artery at the C2 level

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Purpose: To report a case of unilateral segmental agenesis of the vertebral artery (VA). Methods: We describe the angiographic and MRI features of a segmental VA agenesis (C2 segment). Results: VA agenesis is caused by the absence of the anastomotic connection normally linking two adjacent intersegmental arteries; in the reported observation, a paravertebral extraforaminal anastomosis replaced the C2 segment normally joining the 1st and 2nd cervical intersegmental arteries through the C2 transverse foramen. Conclusion: We present an observation of segmental VA agenesis. This variant is consistent with the developmental history of the VA. It appears exceptional but is more likely underappreciated.

Original languageEnglish (US)
Pages (from-to)189-192
Number of pages4
JournalSurgical and Radiologic Anatomy
Issue number2
StatePublished - Feb 1 2020


  • Anatomical variation
  • Angiography
  • Arteries
  • Vertebral artery

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine
  • Radiology Nuclear Medicine and imaging


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