Uniform distribution of projection data for improved reconstruction quality of 4D EPR imaging

Rizwan Ahmad, Deepti S. Vikram, Bradley Clymer, Lee C. Potter, Yuanmu Deng, Parthasarathy Srinivasan, Jay L. Zweier, Periannan Kuppusamy

Research output: Contribution to journalArticle

Abstract

In continuous wave (CW) electron paramagnetic resonance imaging (EPRI), high quality of reconstruction in a limited acquisition time is a high priority. It has been shown for the case of 3D EPRI, that a uniform distribution of the projection data generally enhances reconstruction quality. In this work, we have suggested two data acquisition techniques for which the gradient orientations are more evenly distributed over the 4D acquisition space as compared to the existing methods. The first sampling technique is based on equal solid angle partitioning of 4D space, while the second technique is based on Fekete points estimation in 4D to generate a more uniform distribution of data. After acquisition, filtered backprojection (FBP) is applied to carryout the reconstruction in a single stage. The single-stage reconstruction improves the spatial resolution by eliminating the necessity of data interpolation in multi-stage reconstructions. For the proposed data distributions, the simulations and experimental results indicate a higher fidelity to the true object configuration. Using the uniform distribution, we expect about 50% reduction in the acquisition time over the traditional method of equal linear angle acquisition.

Original languageEnglish (US)
Pages (from-to)277-287
Number of pages11
JournalJournal of Magnetic Resonance
Volume187
Issue number2
DOIs
StatePublished - Aug 2007
Externally publishedYes

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Keywords

  • 4D inverse Radon transform
  • EPRI
  • Fekete points
  • Reconstruction artifacts
  • Single-stage reconstruction

ASJC Scopus subject areas

  • Molecular Biology
  • Physical and Theoretical Chemistry
  • Spectroscopy
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

Cite this

Ahmad, R., Vikram, D. S., Clymer, B., Potter, L. C., Deng, Y., Srinivasan, P., Zweier, J. L., & Kuppusamy, P. (2007). Uniform distribution of projection data for improved reconstruction quality of 4D EPR imaging. Journal of Magnetic Resonance, 187(2), 277-287. https://doi.org/10.1016/j.jmr.2007.05.012