Unexpected cyanosis in the surgical patient.

J. S. Lee, P. A. Mendez, H. O. Douglass

Research output: Contribution to journalArticle


Benzocaine is a commonly used topical anesthetic present in many over-the-counter preparations. The development of methemoglobinemia, associated with the use of benzocaine, is potentially fatal. Methemoglobinemia remains unresponsive to the administration of oxygen alone and, in fact, results in greater tissue hypoxemia than the usual monitoring techniques indicate. We report two cases of benzocaine-induced methemoglobinemia occurring 3 months apart at the same institution. A brief discussion regarding methemoglobin is presented.

Original languageEnglish (US)
Number of pages1
JournalSurgical endoscopy
Issue number6
StatePublished - Jun 2000
Externally publishedYes


ASJC Scopus subject areas

  • Surgery

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