Understanding cognitive dysfunction in multiple sclerosis: Integrating a first-person perspective with neuropsychological testing, neuroimaging, and cognitive neuroscience research

Research output: Contribution to journalReview articlepeer-review

Abstract

This paper gives perspectives on a companion article, the case history of a professional writer who has multiple sclerosis. The patient's first-person account of her illness is combined with clinical summaries about her care. The discussion of this case illustrates the value of combining such subjective and objective reports in evaluating a patient. Furthermore, considering these reports in the context of current research findings on the organization and function of cognitive neural systems can shed light on patients' seemingly contradictory clinical findings. For this patient, a deficit in the ability to select the most important information to achieve her current goals reflected her neuropsychological test results and neuroradiologic findings, and helped to explain her difficulties with her job and her activities of daily living. Because the patient's cognitive impairments have been her primary manifestations of multiple sclerosis, she illustrates the importance of physicians attending to and helping patients manage their cognitive deficits.

Original languageEnglish (US)
Pages (from-to)227-230
Number of pages4
JournalCognitive and Behavioral Neurology
Volume24
Issue number4
DOIs
StatePublished - Dec 2011

Keywords

  • attention
  • multiple sclerosis
  • parietal
  • prefrontal
  • working memory

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Cognitive Neuroscience
  • Psychiatry and Mental health

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