Uncommon high-risk lesions of the breast diagnosed at stereotactic core-needle biopsy: Clinical importance

L. E. Philpotts, N. A. Shaheen, K. S. Jain, D. Carter, C. H. Lee

Research output: Contribution to journalArticle

Abstract

PURPOSE: To assess the outcome of papillary lesions, radial scars, or lobular carcinoma in situ (LCIS) diagnosed at stereotactic core-needle biopsy (SCNB). MATERIALS AND METHODS: Retrospective review of 1,236 lesions sampled with SCNB yielded 22 papillary lesions, nine radial scars, and five LCIS lesions. Diffuse lesions such as papillomatosis, papillary ductal hyperplasia, papillary ductal carcinoma in situ (DCIS), and atypical lobular hyperplasia were not included. The mammographic findings, associated histologic features, and outcome were assessed for each case. RESULTS: Sixteen papillary lesions were diagnosed as benign at SCNB. Of these, five were benign at excision, and 10 were unremarkable at mammographic follow-up. At excision of an unusual lesion containing a microscopic papillary lesion, DCIS was found. Three of four papillary lesions suspicious at SCNB proved to be papillary carcinomas; the fourth had no residual carcinoma at excision. Eight of nine radial scars were excised, which revealed atypical hyperplasia in four scars but no malignancies. One LCIS lesion was found at excision to contain DCIS. CONCLUSION: Benign or malignant papillary lesions were accurately diagnosed with SCNB in the majority of cases. Cases diagnosed as suspicious for malignancy or with atypia or unusual associated histologic findings should be excised. No malignancies were found at excision of radial scars diagnosed at SCNB. Surgical removal of these lesions following SCNB may not be routinely necessary. DCIS was found in one lesion diagnosed as LCIS at SCNB, which suggests that removal of these lesions may be prudent.

Original languageEnglish (US)
Pages (from-to)831-837
Number of pages7
JournalRadiology
Volume216
Issue number3
StatePublished - 2000
Externally publishedYes

Fingerprint

Large-Core Needle Biopsy
Breast
Carcinoma, Intraductal, Noninfiltrating
Cicatrix
Hyperplasia
Papillary Carcinoma
Neoplasms
Papilloma
Carcinoma
Breast Carcinoma In Situ

Keywords

  • Breast neoplasms, diagnosis
  • Breast, biopsy
  • Breast, diseases
  • Breast, radial scar

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Philpotts, L. E., Shaheen, N. A., Jain, K. S., Carter, D., & Lee, C. H. (2000). Uncommon high-risk lesions of the breast diagnosed at stereotactic core-needle biopsy: Clinical importance. Radiology, 216(3), 831-837.

Uncommon high-risk lesions of the breast diagnosed at stereotactic core-needle biopsy : Clinical importance. / Philpotts, L. E.; Shaheen, N. A.; Jain, K. S.; Carter, D.; Lee, C. H.

In: Radiology, Vol. 216, No. 3, 2000, p. 831-837.

Research output: Contribution to journalArticle

Philpotts, LE, Shaheen, NA, Jain, KS, Carter, D & Lee, CH 2000, 'Uncommon high-risk lesions of the breast diagnosed at stereotactic core-needle biopsy: Clinical importance', Radiology, vol. 216, no. 3, pp. 831-837.
Philpotts LE, Shaheen NA, Jain KS, Carter D, Lee CH. Uncommon high-risk lesions of the breast diagnosed at stereotactic core-needle biopsy: Clinical importance. Radiology. 2000;216(3):831-837.
Philpotts, L. E. ; Shaheen, N. A. ; Jain, K. S. ; Carter, D. ; Lee, C. H. / Uncommon high-risk lesions of the breast diagnosed at stereotactic core-needle biopsy : Clinical importance. In: Radiology. 2000 ; Vol. 216, No. 3. pp. 831-837.
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