Un-explained visual loss following silicone oil removal: Results of the Pan American Collaborative Retina Study (PACORES) Group

Jose A. Roca; Lihteh Wu; Maria Berrocal; Francisco Rodriguez; Arturo Alezzandrini; Gustavo Alvira; Raul Velez-Montoya; Hugo Quiroz-Mercado; J. Fernando Arevalo; Martín Serrano; Luiz H. Lima; Marta Figueroa; Michel Farah; Giovanna Chico

doi:10.1186/s40942-017-0079-6

Un-explained visual loss following silicone oil removal: Results of the Pan American Collaborative Retina Study (PACORES) Group

Jose A. Roca, Lihteh Wu, Maria Berrocal, Francisco Rodriguez, Arturo Alezzandrini, Gustavo Alvira, Raul Velez-Montoya, Hugo Quiroz-Mercado, J. Fernando Arevalo, Martín Serrano, Luiz H. Lima, Marta Figueroa, Michel Farah, Giovanna Chico

School of Medicine

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Purpose: To report the incidence and clinical features of patients that experienced un-explained visual loss following silicone oil (SO) removal. Methods: Multicenter retrospective study of patients that underwent SO removal during 2000-2012. Visual loss of ≥2 lines was considered significant. Results: A total of 324 eyes of 324 patients underwent SO removal during the study period. Forty two (13%) eyes suffered a significant visual loss following SO removal. Twenty three (7.1%) of these eyes lost vision secondary to known causes. In the remaining 19 (5.9%) eyes, the loss of vision was not explained by any other pathology. Eleven of these 19 patients (57.9%) were male. The mean age of this group was 49.2 ± 16.4 years. Eyes that had an un-explained visual loss had a mean IOP while the eye was filled with SO of 19.6 ± 6.9 mm Hg. The length of time that the eye was filled with SO was 14.8 ± 4.4 months. In comparison, eyes that did not experience visual loss had a mean IOP of 14 ± 7.3 mm Hg (p < 0.0002) and a mean tamponade duration of 9.3 ± 10.9 months (p < 0.0001). Conclusions: An un-explained visual loss after SO removal was observed in 5.9% of eyes. Factors associated with this phenomenon included a higher IOP and longer SO tamponade duration.

Original language	English (US)
Article number	26
Journal	International Journal of Retina and Vitreous
Volume	3
Issue number	1
DOIs	https://doi.org/10.1186/s40942-017-0079-6
State	Published - 2017

Keywords

Müller cells
Neuronal apoptosis
Potassium
Retinal detachment
Silicone oil
Un-explained visual loss
Vitrectomy

ASJC Scopus subject areas

Ophthalmology

Access to Document

10.1186/s40942-017-0079-6

Cite this

Roca, J. A., Wu, L., Berrocal, M., Rodriguez, F., Alezzandrini, A., Alvira, G., Velez-Montoya, R., Quiroz-Mercado, H., Fernando Arevalo, J., Serrano, M., Lima, L. H., Figueroa, M., Farah, M., & Chico, G. (2017). Un-explained visual loss following silicone oil removal: Results of the Pan American Collaborative Retina Study (PACORES) Group. International Journal of Retina and Vitreous, 3(1), Article 26. https://doi.org/10.1186/s40942-017-0079-6

Roca, JA, Wu, L, Berrocal, M, Rodriguez, F, Alezzandrini, A, Alvira, G, Velez-Montoya, R, Quiroz-Mercado, H, Fernando Arevalo, J, Serrano, M, Lima, LH, Figueroa, M, Farah, M & Chico, G 2017, 'Un-explained visual loss following silicone oil removal: Results of the Pan American Collaborative Retina Study (PACORES) Group', International Journal of Retina and Vitreous, vol. 3, no. 1, 26. https://doi.org/10.1186/s40942-017-0079-6

@article{a746a1407b1a4cafb9de35683e3944ec,

title = "Un-explained visual loss following silicone oil removal: Results of the Pan American Collaborative Retina Study (PACORES) Group",

abstract = "Purpose: To report the incidence and clinical features of patients that experienced un-explained visual loss following silicone oil (SO) removal. Methods: Multicenter retrospective study of patients that underwent SO removal during 2000-2012. Visual loss of ≥2 lines was considered significant. Results: A total of 324 eyes of 324 patients underwent SO removal during the study period. Forty two (13%) eyes suffered a significant visual loss following SO removal. Twenty three (7.1%) of these eyes lost vision secondary to known causes. In the remaining 19 (5.9%) eyes, the loss of vision was not explained by any other pathology. Eleven of these 19 patients (57.9%) were male. The mean age of this group was 49.2 ± 16.4 years. Eyes that had an un-explained visual loss had a mean IOP while the eye was filled with SO of 19.6 ± 6.9 mm Hg. The length of time that the eye was filled with SO was 14.8 ± 4.4 months. In comparison, eyes that did not experience visual loss had a mean IOP of 14 ± 7.3 mm Hg (p < 0.0002) and a mean tamponade duration of 9.3 ± 10.9 months (p < 0.0001). Conclusions: An un-explained visual loss after SO removal was observed in 5.9% of eyes. Factors associated with this phenomenon included a higher IOP and longer SO tamponade duration.",

keywords = "M{\"u}ller cells, Neuronal apoptosis, Potassium, Retinal detachment, Silicone oil, Un-explained visual loss, Vitrectomy",

author = "Roca, {Jose A.} and Lihteh Wu and Maria Berrocal and Francisco Rodriguez and Arturo Alezzandrini and Gustavo Alvira and Raul Velez-Montoya and Hugo Quiroz-Mercado and {Fernando Arevalo}, J. and Mart{\'i}n Serrano and Lima, {Luiz H.} and Marta Figueroa and Michel Farah and Giovanna Chico",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2017.",

year = "2017",

doi = "10.1186/s40942-017-0079-6",

language = "English (US)",

volume = "3",

journal = "International Journal of Retina and Vitreous",

issn = "2056-9920",

publisher = "BioMed Central Ltd.",

number = "1",

}

TY - JOUR

T1 - Un-explained visual loss following silicone oil removal

T2 - Results of the Pan American Collaborative Retina Study (PACORES) Group

AU - Roca, Jose A.

AU - Wu, Lihteh

AU - Berrocal, Maria

AU - Rodriguez, Francisco

AU - Alezzandrini, Arturo

AU - Alvira, Gustavo

AU - Velez-Montoya, Raul

AU - Quiroz-Mercado, Hugo

AU - Fernando Arevalo, J.

AU - Serrano, Martín

AU - Lima, Luiz H.

AU - Figueroa, Marta

AU - Farah, Michel

AU - Chico, Giovanna

N1 - Publisher Copyright: © The Author(s) 2017.

PY - 2017

Y1 - 2017

N2 - Purpose: To report the incidence and clinical features of patients that experienced un-explained visual loss following silicone oil (SO) removal. Methods: Multicenter retrospective study of patients that underwent SO removal during 2000-2012. Visual loss of ≥2 lines was considered significant. Results: A total of 324 eyes of 324 patients underwent SO removal during the study period. Forty two (13%) eyes suffered a significant visual loss following SO removal. Twenty three (7.1%) of these eyes lost vision secondary to known causes. In the remaining 19 (5.9%) eyes, the loss of vision was not explained by any other pathology. Eleven of these 19 patients (57.9%) were male. The mean age of this group was 49.2 ± 16.4 years. Eyes that had an un-explained visual loss had a mean IOP while the eye was filled with SO of 19.6 ± 6.9 mm Hg. The length of time that the eye was filled with SO was 14.8 ± 4.4 months. In comparison, eyes that did not experience visual loss had a mean IOP of 14 ± 7.3 mm Hg (p < 0.0002) and a mean tamponade duration of 9.3 ± 10.9 months (p < 0.0001). Conclusions: An un-explained visual loss after SO removal was observed in 5.9% of eyes. Factors associated with this phenomenon included a higher IOP and longer SO tamponade duration.

AB - Purpose: To report the incidence and clinical features of patients that experienced un-explained visual loss following silicone oil (SO) removal. Methods: Multicenter retrospective study of patients that underwent SO removal during 2000-2012. Visual loss of ≥2 lines was considered significant. Results: A total of 324 eyes of 324 patients underwent SO removal during the study period. Forty two (13%) eyes suffered a significant visual loss following SO removal. Twenty three (7.1%) of these eyes lost vision secondary to known causes. In the remaining 19 (5.9%) eyes, the loss of vision was not explained by any other pathology. Eleven of these 19 patients (57.9%) were male. The mean age of this group was 49.2 ± 16.4 years. Eyes that had an un-explained visual loss had a mean IOP while the eye was filled with SO of 19.6 ± 6.9 mm Hg. The length of time that the eye was filled with SO was 14.8 ± 4.4 months. In comparison, eyes that did not experience visual loss had a mean IOP of 14 ± 7.3 mm Hg (p < 0.0002) and a mean tamponade duration of 9.3 ± 10.9 months (p < 0.0001). Conclusions: An un-explained visual loss after SO removal was observed in 5.9% of eyes. Factors associated with this phenomenon included a higher IOP and longer SO tamponade duration.

KW - Müller cells

KW - Neuronal apoptosis

KW - Potassium

KW - Retinal detachment

KW - Silicone oil

KW - Un-explained visual loss

KW - Vitrectomy

UR - http://www.scopus.com/inward/record.url?scp=85046785288&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85046785288&partnerID=8YFLogxK

U2 - 10.1186/s40942-017-0079-6

DO - 10.1186/s40942-017-0079-6

M3 - Article

C2 - 28748109

AN - SCOPUS:85046785288

SN - 2056-9920

VL - 3

JO - International Journal of Retina and Vitreous

JF - International Journal of Retina and Vitreous

IS - 1

M1 - 26

ER -

Un-explained visual loss following silicone oil removal: Results of the Pan American Collaborative Retina Study (PACORES) Group

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this