Ultrastructure of the gastric mucosa harboring Campylobacter-like organisms

X. G. Chen, P. Correa, J. Offerhaus, E. Rodriguez, F. Janney, E. Hoffmann, J. Fox, F. Hunter, S. Diavolitsis

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Abstract

The association between Campylobacter-like organisms (CLOs) and lesions of the gastric mucosa was studied in 59 consecutive biopsies. Hematoxylin and eosin and Warthin-Starry silver stains, as well as high-resolution light microscopy (HRLM) and transmission electron microscopy (TEM), were used. The organisms were found in intimate contact with foveolar cells showing abundant phagolysosomes and alterations of the intercellular complexes. CLOs also were seen in close proximity of parietal cells in resting phase, some of which showed degenerative changes. The findings are discussed in light of recent reports linking CLOs to the cause of gastritis.

Original languageEnglish (US)
Pages (from-to)575-582
Number of pages8
JournalAmerican Journal of Clinical Pathology
Volume86
Issue number5
StatePublished - 1986
Externally publishedYes

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ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Chen, X. G., Correa, P., Offerhaus, J., Rodriguez, E., Janney, F., Hoffmann, E., Fox, J., Hunter, F., & Diavolitsis, S. (1986). Ultrastructure of the gastric mucosa harboring Campylobacter-like organisms. American Journal of Clinical Pathology, 86(5), 575-582.