Abstract
The presence of Fos-labeled neurons at ultrastructural level was confirmed in the spinal superficial laminae following an injection of formalin into rat hindpaw in the present study. The Fos-like immunoreactive products were found exclusively in regions associated with the euchromatin in the nuclei of Fos-labeled neurons. By the methods used - of anterograde transport of horseradish peroxidase conjugated to wheat-germ agglutinin and immunocytochemistry - it was observed that some Fos-labeled neuronal bodies received synaptic contacts from, or were apposed directly to, small diameter primary afferent terminals in the spinal superficial laminae. By means of double-labeled immunocytochemistry, a direct apposition was often observed and a synaptic relationship was occasionally found between Fos-labeled neuronal bodies and substance P-like immunoreactive terminals.
Original language | English (US) |
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Pages (from-to) | 327-332 |
Number of pages | 6 |
Journal | Neuropeptides |
Volume | 31 |
Issue number | 4 |
DOIs | |
State | Published - 1997 |
ASJC Scopus subject areas
- Endocrinology
- Neurology
- Endocrine and Autonomic Systems
- Cellular and Molecular Neuroscience