TY - JOUR
T1 - Ultrasound-guided characterization of interstitial ablated tissue using RF time series
T2 - Feasibility study
AU - Imani, Farhad
AU - Abolmaesumi, Purang
AU - Wu, Mark Z.
AU - Lasso, Andras
AU - Burdette, Everett C.
AU - Ghoshal, Goutam
AU - Heffter, Tamas
AU - Williams, Emery
AU - Neubauer, Paul
AU - Fichtinger, Gabor
AU - Mousavi, Parvin
PY - 2013
Y1 - 2013
N2 - This paper presents the results of a feasibility study to demonstrate the application of ultrasound RF time series imaging to accurately differentiate ablated and nonablated tissue. For 12 ex vivo and two in situ tissue samples, RF ultrasound signals are acquired prior to, and following, high-intensity ultrasound ablation. Spatial and temporal features of these signals are used to characterize ablated and nonablated tissue in a supervised-learning framework. In cross-validation evaluation, a subset of four features extracted from RF time series produce a classification accuracy of 84.5%, an area under ROC curve of 0.91 for ex vivo data, and an accuracy of 85% for in situ data. Ultrasound RF time series is a promising approach for characterizing ablated tissue.
AB - This paper presents the results of a feasibility study to demonstrate the application of ultrasound RF time series imaging to accurately differentiate ablated and nonablated tissue. For 12 ex vivo and two in situ tissue samples, RF ultrasound signals are acquired prior to, and following, high-intensity ultrasound ablation. Spatial and temporal features of these signals are used to characterize ablated and nonablated tissue in a supervised-learning framework. In cross-validation evaluation, a subset of four features extracted from RF time series produce a classification accuracy of 84.5%, an area under ROC curve of 0.91 for ex vivo data, and an accuracy of 85% for in situ data. Ultrasound RF time series is a promising approach for characterizing ablated tissue.
KW - Characterization of ablated tissue region
KW - tissue ablation
KW - ultrasound RF time series
UR - http://www.scopus.com/inward/record.url?scp=84877903060&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84877903060&partnerID=8YFLogxK
U2 - 10.1109/TBME.2013.2240300
DO - 10.1109/TBME.2013.2240300
M3 - Article
C2 - 23335657
AN - SCOPUS:84877903060
SN - 0018-9294
VL - 60
SP - 1608
EP - 1618
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
IS - 6
M1 - 6412777
ER -