@inproceedings{07202495c3564b7e9b8daf9ee8a3af00,
title = "Ultrasound elastography - enabling technology for image guided laparoscopic prostatectomy",
abstract = "Radical prostatectomy using the laparoscopic and robot-assisted approach lacks tactile feedback. Without palpation, the surgeon needs an affordable imaging technology which can be easily incorporated into the laparoscopic surgical procedure, allowing for precise real time intraoperative tumor localization that will guide the extent of surgical resection. Ultrasound elastography (USE) is a novel ultrasound imaging technology that can detect differences in tissue density or stiffness based on tissue deformation. USE was evaluated here as an enabling technology for image guided laparoscopic prostatectomy. USE using a 2D Dynamic Programming (DP) algorithm was applied on data from ex vivo human prostate specimens. It proved consistent in identification of lesions; hard and soft, malignant and benign, located in the prostate's central gland or in the peripheral zone. We noticed the 2D DP method was able to generate low-noise elastograms using two frames belonging to the same compression or relaxation part of the palpation excitation, even at compression rates up to 10%. Good preliminary results were validated by pathology findings, and also by in vivo and ex vivo MR imaging. We also evaluated the use of ultrasound elastography for imaging cavernous nerves; here we present data from animal model experiments.",
keywords = "Cavernous nerves, Elastography, Laparoscopic prostatectomy, Nerve imaging, Prostate, ultrasound",
author = "Fleming, {Ioana N.} and Hassan Rivaz and Katarzyna Macura and Suc, {Li Ming} and Ulrike Hamper and Lagoda, {Gwen A.} and Burnett, {Arthur L.} and {Lotan Tamara}, Tamara and Taylor, {Russell H.} and Hager, {Gregory D.} and Boctor, {Emad M.}",
year = "2009",
doi = "10.1117/12.806507",
language = "English (US)",
isbn = "9780819475121",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Medical Imaging 2009",
note = "Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging ; Conference date: 08-02-2009 Through 10-02-2009",
}