TY - JOUR
T1 - Ultrafast acquisition of localized two-dimensional magnetic resonance correlated spectra of inhomogeneous biological tissues with resolution improvements
AU - Wei, Zhiliang
AU - Lin, Liangjie
AU - Lin, Yanqin
AU - Cai, Shuhui
AU - Chen, Zhong
N1 - Funding Information:
This work was partially supported by the NNSF of China under Grants 11105114 and 11174239 , and the Fundamental Research Funds for the Central Universities under Grant 2010121010 . The authors thank Prof. Tien-Mo Shih for linguistic assistance.
Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2013/8/21
Y1 - 2013/8/21
N2 - Long acquisition time and strict requests of homogeneous magnetic fields restrain wide applications of localized 2D magnetic resonance spectroscopy. Here, a pulse sequence utilizing the spatial encoding technique and spin echo is proposed to obtain localized 2D correlated spectra with resolution improvements under inhomogeneous fields within greatly reduced times. The localized correlated spectrum of pig marrow obtained with the proposed scheme retained more information compared to the conventional spectrum. The method proposed herein offers important perspectives for fast in vivo analyses of metabolites in living inhomogeneous organisms and in situ characterization of intermediates of inhomogeneous chemical reaction systems.
AB - Long acquisition time and strict requests of homogeneous magnetic fields restrain wide applications of localized 2D magnetic resonance spectroscopy. Here, a pulse sequence utilizing the spatial encoding technique and spin echo is proposed to obtain localized 2D correlated spectra with resolution improvements under inhomogeneous fields within greatly reduced times. The localized correlated spectrum of pig marrow obtained with the proposed scheme retained more information compared to the conventional spectrum. The method proposed herein offers important perspectives for fast in vivo analyses of metabolites in living inhomogeneous organisms and in situ characterization of intermediates of inhomogeneous chemical reaction systems.
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U2 - 10.1016/j.cplett.2013.07.015
DO - 10.1016/j.cplett.2013.07.015
M3 - Article
AN - SCOPUS:84881481805
SN - 0009-2614
VL - 581
SP - 96
EP - 102
JO - Chemical Physics Letters
JF - Chemical Physics Letters
ER -