Ultrafast acquisition of localized two-dimensional magnetic resonance correlated spectra of inhomogeneous biological tissues with resolution improvements

Zhiliang Wei, Liangjie Lin, Yanqin Lin, Shuhui Cai, Zhong Chen

Research output: Contribution to journalArticle

Abstract

Long acquisition time and strict requests of homogeneous magnetic fields restrain wide applications of localized 2D magnetic resonance spectroscopy. Here, a pulse sequence utilizing the spatial encoding technique and spin echo is proposed to obtain localized 2D correlated spectra with resolution improvements under inhomogeneous fields within greatly reduced times. The localized correlated spectrum of pig marrow obtained with the proposed scheme retained more information compared to the conventional spectrum. The method proposed herein offers important perspectives for fast in vivo analyses of metabolites in living inhomogeneous organisms and in situ characterization of intermediates of inhomogeneous chemical reaction systems.

Original languageEnglish (US)
Pages (from-to)96-102
Number of pages7
JournalChemical Physics Letters
Volume581
DOIs
StatePublished - Aug 21 2013
Externally publishedYes

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Magnetic resonance spectroscopy
Magnetic resonance
Metabolites
magnetic resonance
Chemical reactions
acquisition
Tissue
Magnetic fields
swine
metabolites
magnetic resonance spectroscopy
organisms
chemical reactions
echoes
coding
pulses
magnetic fields

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

Cite this

Ultrafast acquisition of localized two-dimensional magnetic resonance correlated spectra of inhomogeneous biological tissues with resolution improvements. / Wei, Zhiliang; Lin, Liangjie; Lin, Yanqin; Cai, Shuhui; Chen, Zhong.

In: Chemical Physics Letters, Vol. 581, 21.08.2013, p. 96-102.

Research output: Contribution to journalArticle

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