Abstract
Objective To evaluate the association between ultra-processed food intake and all-cause mortality and CVD mortality in a nationally representative sample of US adults.Design Prospective analyses of reported frequency of ultra-processed food intake in 1988-1994 and all-cause mortality and CVD mortality through 2011.Setting The Third National Health and Nutrition Examination Survey (NHANES III, 1988-1994).Participants Adults aged ≥20 years (n 11898).Results Over a median follow-up of 19 years, individuals in the highest quartile of frequency of ultra-processed food intake (e.g. sugar-sweetened or artificially sweetened beverages, sweetened milk, sausage or other reconstructed meats, sweetened cereals, confectionery, desserts) had a 31% higher risk of all-cause mortality, after adjusting for demographic and socio-economic confounders and health behaviours (adjusted hazard ratio=1·31; 95% CI 1·09, 1·58; P-trend = 0·001). No association with CVD mortality was observed (P-trend=0·86).Conclusions Higher frequency of ultra-processed food intake was associated with higher risk of all-cause mortality in a representative sample of US adults. More longitudinal studies with dietary data reflecting the modern food supply are needed to confirm our results.
Original language | English (US) |
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Pages (from-to) | 1777-1785 |
Number of pages | 9 |
Journal | Public health nutrition |
Volume | 22 |
Issue number | 10 |
DOIs | |
State | Published - Jul 1 2019 |
Keywords
- Mortality
- NOVA classification
- Nutritional characteristics
- Nutritional quality
- Ultra-processed food
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics
- Public Health, Environmental and Occupational Health