Abstract
A patient who had hereditary tyrosinemia was observed during two illnesses to have characteristics ofacute intermittent porphyria with associated hypertension. Metabolic studies revealed elevated levels of urinary aminolevulinic acid but normal levels of porphyrin metabolites associated with, and possibly explained by, decreased red blood cell activity of the zinc-dependent enzyme, aminolevulinic acid dehydratase. Zinc deficiency could not be directly associated with the diminished enzyme activity. The patient's hypertension appeared to be related to increased urinary excretion of catecholamines and to elevated renin activity in peripheral venous blood.
Original language | English (US) |
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Pages (from-to) | 400-404 |
Number of pages | 5 |
Journal | The Journal of pediatrics |
Volume | 90 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1977 |
Externally published | Yes |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health