Type II DNA topoisomerases

Research output: Contribution to journalArticle

Abstract

Type II DNA topoisomerases are enzymes capable of passing one DNA duplex through another. A combination of structural and biochemical analyses is illuminating the mechanistic details of this transport reaction, revealing the sites of DNA and nucleotide binding and the existence of large-scale domain motions.

Original languageEnglish (US)
Pages (from-to)26-32
Number of pages7
JournalCurrent Opinion in Structural Biology
Volume8
Issue number1
DOIs
StatePublished - Feb 1998
Externally publishedYes

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Type II DNA Topoisomerase
DNA
Nucleotides
Enzymes

ASJC Scopus subject areas

  • Molecular Biology
  • Structural Biology

Cite this

Type II DNA topoisomerases. / Berger, James M.

In: Current Opinion in Structural Biology, Vol. 8, No. 1, 02.1998, p. 26-32.

Research output: Contribution to journalArticle

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