Abstract
A new class of nuclear magnetic resonance (NMR) pulses that provides simultaneous spatially selective inversion of nuclear spins in two dimensions following a single pulse application is described and demonstrated. The two-dimensional selective pulses consist of a single square- or amplitude-modulated π rf pulse applied in the presence of an amplitude-modulated magnetic field gradient that reorients through the two dimensions during the rf pulse. For example, square and Gaussian rf pulses produce sharply peaked sombrero-, egg-carton-, and stalagmite-shaped profiles of spin inversion in the xz plane when applied in the presence of a gradient that rotates or describes a figure eight in the xz plane. The theoretical profiles, computed by numerical integration of the Bloch equation, are in good agreement with experimental results obtained by incorporating the pulses into a conventional NMR imaging sequence. The pulses are directly applicable to restricted field-of-view high-resolution imaging for the amelioration of aliasing signal artifacts, and when combined with one-dimensional localized phosphorus (31P) chemical shift spectroscopy techniques that employ surface detection coils, should permit complete three-dimensionally localized 31P NMR spectroscopy. The π pulses provide similar two-dimensional spatial selectivity of the transverse nuclear magnetization when used for refocusing Hahn spin echoes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4284-4290 |
| Number of pages | 7 |
| Journal | Journal of Applied Physics |
| Volume | 62 |
| Issue number | 10 |
| DOIs | |
| State | Published - 1987 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Physics and Astronomy (miscellaneous)
Cite this
Two-dimensional spatially selective spin inversion and spin-echo refocusing with a single nuclear magnetic resonance pulse. / Bottomley, Paul A; Hardy, Christopher J.
In: Journal of Applied Physics, Vol. 62, No. 10, 1987, p. 4284-4290.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Two-dimensional spatially selective spin inversion and spin-echo refocusing with a single nuclear magnetic resonance pulse
AU - Bottomley, Paul A
AU - Hardy, Christopher J.
PY - 1987
Y1 - 1987
N2 - A new class of nuclear magnetic resonance (NMR) pulses that provides simultaneous spatially selective inversion of nuclear spins in two dimensions following a single pulse application is described and demonstrated. The two-dimensional selective pulses consist of a single square- or amplitude-modulated π rf pulse applied in the presence of an amplitude-modulated magnetic field gradient that reorients through the two dimensions during the rf pulse. For example, square and Gaussian rf pulses produce sharply peaked sombrero-, egg-carton-, and stalagmite-shaped profiles of spin inversion in the xz plane when applied in the presence of a gradient that rotates or describes a figure eight in the xz plane. The theoretical profiles, computed by numerical integration of the Bloch equation, are in good agreement with experimental results obtained by incorporating the pulses into a conventional NMR imaging sequence. The pulses are directly applicable to restricted field-of-view high-resolution imaging for the amelioration of aliasing signal artifacts, and when combined with one-dimensional localized phosphorus (31P) chemical shift spectroscopy techniques that employ surface detection coils, should permit complete three-dimensionally localized 31P NMR spectroscopy. The π pulses provide similar two-dimensional spatial selectivity of the transverse nuclear magnetization when used for refocusing Hahn spin echoes.
AB - A new class of nuclear magnetic resonance (NMR) pulses that provides simultaneous spatially selective inversion of nuclear spins in two dimensions following a single pulse application is described and demonstrated. The two-dimensional selective pulses consist of a single square- or amplitude-modulated π rf pulse applied in the presence of an amplitude-modulated magnetic field gradient that reorients through the two dimensions during the rf pulse. For example, square and Gaussian rf pulses produce sharply peaked sombrero-, egg-carton-, and stalagmite-shaped profiles of spin inversion in the xz plane when applied in the presence of a gradient that rotates or describes a figure eight in the xz plane. The theoretical profiles, computed by numerical integration of the Bloch equation, are in good agreement with experimental results obtained by incorporating the pulses into a conventional NMR imaging sequence. The pulses are directly applicable to restricted field-of-view high-resolution imaging for the amelioration of aliasing signal artifacts, and when combined with one-dimensional localized phosphorus (31P) chemical shift spectroscopy techniques that employ surface detection coils, should permit complete three-dimensionally localized 31P NMR spectroscopy. The π pulses provide similar two-dimensional spatial selectivity of the transverse nuclear magnetization when used for refocusing Hahn spin echoes.
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U2 - 10.1063/1.339103
DO - 10.1063/1.339103
M3 - Article
AN - SCOPUS:0347361501
VL - 62
SP - 4284
EP - 4290
JO - Journal of Applied Physics
JF - Journal of Applied Physics
SN - 0021-8979
IS - 10
ER -