Abstract
Purpose: To report the efficacy of intravitreal bevacizumab (IVB) injection versus intravitreal triamcinolone acetonide (IVT) for persistent non-infectious uveitic cystoid macular edema (CME). Methods: Interventional retrospective comparative case series evaluated 37 consecutive patients (44 eyes) with completely controlled uveitis and recalcitrant CME. Patients received repeated injections of 1.25 mg of IVB or 4 mg of IVT. Results: Best-corrected visual acuity (BCVA) at baseline and 24 months was logMAR 1 and 0.8 respectively, in the IVB group (p = 0.002) and; logMAR of 1.1 and 0.6, in the IVT group (p = 0.001). Central macular thickness at baseline and 24 months was 399.2 µm and 333.7 µm (p < 0.0009), respectively, for the IVB group and; 464.4 µm and 316.5 µm in the IVT group (p = 0.044). Postoperatively, IOP increased in the IVT group. Conclusions: Repeated injections with IVT improve BCVA as effectively as repeated injections with IVB in the long-term management of persistent uveitic CME.
Original language | English (US) |
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Pages (from-to) | 294-302 |
Number of pages | 9 |
Journal | Ocular Immunology and Inflammation |
Volume | 27 |
Issue number | 2 |
DOIs | |
State | Published - Feb 17 2019 |
Keywords
- Bevacizumab
- Intravitreal Injection
- Triamcinolone Acetonide
- Uveitic Cystoid Macular Edema
ASJC Scopus subject areas
- Immunology and Allergy
- Ophthalmology