TY - JOUR
T1 - Tumoral calcinosis in infants
T2 - A report of three cases and review of the literature
AU - Hammoud, Sommer
AU - McCarthy, Edward F.
AU - Weber, Kristy
N1 - Funding Information:
Funding was provided by the Wellcome Trust (SMS, grant 084730), the Henry Smith Charity (SMS), Action Medical Research (SMS), National Institutes of Health (HCM R56NS69605), National Health and Medical Research Council of Australia (SFB, IES), Health Research Council of New Zealand (LGS), The Netherlands National Epilepsy Fund (grant 04-08 to B.P.C.K), German Research Foundation (HE 5415 3-1) within the EuroEPINOMICS framework of the Eurocores program by the European Science Foundation (ESF), intramural funds of the University of Kiel, Germany. H.L., P.N. and T.S. received grants by the EuroEPINOMICS programme (German Research Council, DFG grant numbers: HL: LE1030/11-1; PN: NU50/8-1, TS: SA434/5-1) within the EUROCORES framework of the European Science Foundation (ESF); the collection of the CoGIE cohort was also supported by the EuroEPINOMICS program. Patient collection in Europe was partly made possible thanks to the European FP6 Marie Curie Excellence Grant on Visual Sensitivity MEXCT-CT-2005-024224. CVE is an Industrial Research Fund mandate holder of the KU Leuven. This work was partly undertaken at UCLH/UCL, which received a proportion of funding from the Department of Health’s NIHR Biomedical Research Centres funding scheme.
PY - 2005/7
Y1 - 2005/7
N2 - Tumoral calcinosis is the deposition of calcium crystals and salts in the periarticular soft tissues. It commonly is seen as a complication of renal dialysis or in patients with a hereditary disposition. Occasionally, it is seen as an isolated condition with no known cause. Tumoral calcinosis usually affects adults and rarely, children. This disorder is extremely uncommon in infants. Only 13 cases have been reported. In this study three additional infants with tumoral calcinosis are reported, bringing the total to 16 cases. These 16 cases provide the opportunity to compare tumoral calcinosis in infants (younger than 18 months) with the disease in older patients. Although histologic and radiologic features in infants and adults are identical, some clinical features differ. In almost all infants, the disease develops without any predisposing factors, such as a family history. Surgical removal of lesions in infants is curative. By contrast, lesions in adults tend to recur after surgery.
AB - Tumoral calcinosis is the deposition of calcium crystals and salts in the periarticular soft tissues. It commonly is seen as a complication of renal dialysis or in patients with a hereditary disposition. Occasionally, it is seen as an isolated condition with no known cause. Tumoral calcinosis usually affects adults and rarely, children. This disorder is extremely uncommon in infants. Only 13 cases have been reported. In this study three additional infants with tumoral calcinosis are reported, bringing the total to 16 cases. These 16 cases provide the opportunity to compare tumoral calcinosis in infants (younger than 18 months) with the disease in older patients. Although histologic and radiologic features in infants and adults are identical, some clinical features differ. In almost all infants, the disease develops without any predisposing factors, such as a family history. Surgical removal of lesions in infants is curative. By contrast, lesions in adults tend to recur after surgery.
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U2 - 10.1097/01.blo.0000157040.96980.bd
DO - 10.1097/01.blo.0000157040.96980.bd
M3 - Review article
C2 - 15995450
AN - SCOPUS:21844449993
VL - 436
SP - 261
EP - 264
JO - Clinical Orthopaedics and Related Research
JF - Clinical Orthopaedics and Related Research
SN - 0009-921X
ER -