Tumor Localization of Radio-Labeled Antibodies

David M. Goldenberg; Frank H. Deland; E. Edmund Kim; Stanley E. Order; Peter Leichner; David S. Ettinger; Jerry L. Klein; Mette Strand; R. Begent; K. Bagshawe; G. Stanway; P. Keep; F. Searle; E. Newlands; R. Jewkes; B. Jones; P. Vernon; Jean Pierre Mach; Stephan Carrel; Michel Forni; Jürg Ritschard; Alfred Donath; Pierre Alberto

doi:10.1056/NEJM198011203032117

Tumor Localization of Radio-Labeled Antibodies

David M. Goldenberg, Frank H. Deland, E. Edmund Kim, Stanley E. Order, Peter Leichner, David S. Ettinger, Jerry L. Klein, Mette Strand, R. Begent, K. Bagshawe, G. Stanway, P. Keep, F. Searle, E. Newlands, R. Jewkes, B. Jones, P. Vernon, Jean Pierre Mach, Stephan Carrel, Michel ForniJürg Ritschard, Alfred Donath, Pierre Alberto

School of Medicine

Research output: Contribution to journal › Letter › peer-review

Abstract

To the Editor: We congratulate Mach et al. for their report in the July 3 issue on the unequivocal scintigraphic identification of tumor sites in 11 of 27 patients given [¹³¹I]-labeled antibody to carcinoembryonic antigen (CEA) — a method that has been described as the radioimmunodetection of cancer.¹ This report corrects the authors' previous claim that cancer radioimmunodetection in human beings with radioactive CEA antibodies is not feasible, ² and we ascribe the earlier failure to their not using the computer-assisted background-subtraction method described in our original clinical study of CEA tumor radioimmunodetection.³ Although their paper confirms our report that.

Original language	English (US)
Pages (from-to)	1237-1239
Number of pages	3
Journal	New England Journal of Medicine
Volume	303
Issue number	21
DOIs	https://doi.org/10.1056/NEJM198011203032117
State	Published - Nov 20 1980

ASJC Scopus subject areas

Medicine(all)

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Goldenberg, D. M., Deland, F. H., Kim, E. E., Order, S. E., Leichner, P., Ettinger, D. S., Klein, J. L., Strand, M., Begent, R., Bagshawe, K., Stanway, G., Keep, P., Searle, F., Newlands, E., Jewkes, R., Jones, B., Vernon, P., Mach, J. P., Carrel, S., ... Alberto, P. (1980). Tumor Localization of Radio-Labeled Antibodies. New England Journal of Medicine, 303(21), 1237-1239. https://doi.org/10.1056/NEJM198011203032117

Tumor Localization of Radio-Labeled Antibodies. / Goldenberg, David M.; Deland, Frank H.; Kim, E. Edmund; Order, Stanley E.; Leichner, Peter; Ettinger, David S.; Klein, Jerry L.; Strand, Mette; Begent, R.; Bagshawe, K.; Stanway, G.; Keep, P.; Searle, F.; Newlands, E.; Jewkes, R.; Jones, B.; Vernon, P.; Mach, Jean Pierre; Carrel, Stephan; Forni, Michel; Ritschard, Jürg; Donath, Alfred; Alberto, Pierre.

In: New England Journal of Medicine, Vol. 303, No. 21, 20.11.1980, p. 1237-1239.

Research output: Contribution to journal › Letter › peer-review

Goldenberg, DM, Deland, FH, Kim, EE, Order, SE, Leichner, P, Ettinger, DS, Klein, JL, Strand, M, Begent, R, Bagshawe, K, Stanway, G, Keep, P, Searle, F, Newlands, E, Jewkes, R, Jones, B, Vernon, P, Mach, JP, Carrel, S, Forni, M, Ritschard, J, Donath, A & Alberto, P 1980, 'Tumor Localization of Radio-Labeled Antibodies', New England Journal of Medicine, vol. 303, no. 21, pp. 1237-1239. https://doi.org/10.1056/NEJM198011203032117

Goldenberg, David M. ; Deland, Frank H. ; Kim, E. Edmund ; Order, Stanley E. ; Leichner, Peter ; Ettinger, David S. ; Klein, Jerry L. ; Strand, Mette ; Begent, R. ; Bagshawe, K. ; Stanway, G. ; Keep, P. ; Searle, F. ; Newlands, E. ; Jewkes, R. ; Jones, B. ; Vernon, P. ; Mach, Jean Pierre ; Carrel, Stephan ; Forni, Michel ; Ritschard, Jürg ; Donath, Alfred ; Alberto, Pierre. / Tumor Localization of Radio-Labeled Antibodies. In: New England Journal of Medicine. 1980 ; Vol. 303, No. 21. pp. 1237-1239.

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abstract = "To the Editor: We congratulate Mach et al. for their report in the July 3 issue on the unequivocal scintigraphic identification of tumor sites in 11 of 27 patients given [131I]-labeled antibody to carcinoembryonic antigen (CEA) — a method that has been described as the radioimmunodetection of cancer.1 This report corrects the authors' previous claim that cancer radioimmunodetection in human beings with radioactive CEA antibodies is not feasible, 2 and we ascribe the earlier failure to their not using the computer-assisted background-subtraction method described in our original clinical study of CEA tumor radioimmunodetection.3 Although their paper confirms our report that.",

author = "Goldenberg, {David M.} and Deland, {Frank H.} and Kim, {E. Edmund} and Order, {Stanley E.} and Peter Leichner and Ettinger, {David S.} and Klein, {Jerry L.} and Mette Strand and R. Begent and K. Bagshawe and G. Stanway and P. Keep and F. Searle and E. Newlands and R. Jewkes and B. Jones and P. Vernon and Mach, {Jean Pierre} and Stephan Carrel and Michel Forni and J{\"u}rg Ritschard and Alfred Donath and Pierre Alberto",

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doi = "10.1056/NEJM198011203032117",

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AU - Goldenberg, David M.

AU - Deland, Frank H.

AU - Kim, E. Edmund

AU - Order, Stanley E.

AU - Leichner, Peter

AU - Ettinger, David S.

AU - Klein, Jerry L.

AU - Strand, Mette

AU - Begent, R.

AU - Bagshawe, K.

AU - Stanway, G.

AU - Keep, P.

AU - Searle, F.

AU - Newlands, E.

AU - Jewkes, R.

AU - Jones, B.

AU - Vernon, P.

AU - Mach, Jean Pierre

AU - Carrel, Stephan

AU - Forni, Michel

AU - Ritschard, Jürg

AU - Donath, Alfred

AU - Alberto, Pierre

PY - 1980/11/20

Y1 - 1980/11/20

N2 - To the Editor: We congratulate Mach et al. for their report in the July 3 issue on the unequivocal scintigraphic identification of tumor sites in 11 of 27 patients given [131I]-labeled antibody to carcinoembryonic antigen (CEA) — a method that has been described as the radioimmunodetection of cancer.1 This report corrects the authors' previous claim that cancer radioimmunodetection in human beings with radioactive CEA antibodies is not feasible, 2 and we ascribe the earlier failure to their not using the computer-assisted background-subtraction method described in our original clinical study of CEA tumor radioimmunodetection.3 Although their paper confirms our report that.

AB - To the Editor: We congratulate Mach et al. for their report in the July 3 issue on the unequivocal scintigraphic identification of tumor sites in 11 of 27 patients given [131I]-labeled antibody to carcinoembryonic antigen (CEA) — a method that has been described as the radioimmunodetection of cancer.1 This report corrects the authors' previous claim that cancer radioimmunodetection in human beings with radioactive CEA antibodies is not feasible, 2 and we ascribe the earlier failure to their not using the computer-assisted background-subtraction method described in our original clinical study of CEA tumor radioimmunodetection.3 Although their paper confirms our report that.

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Tumor Localization of Radio-Labeled Antibodies

Abstract

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