Tumor Localization of Radio-Labeled Antibodies

David M. Goldenberg, Frank H. Deland, E. Edmund Kim, Stanley E. Order, Peter Leichner, David S. Ettinger, Jerry L. Klein, Mette Strand, R. Begent, K. Bagshawe, G. Stanway, P. Keep, F. Searle, E. Newlands, R. Jewkes, B. Jones, P. Vernon, Jean Pierre Mach, Stephan Carrel, Michel ForniJürg Ritschard, Alfred Donath, Pierre Alberto

Research output: Contribution to journalLetterpeer-review

Abstract

To the Editor: We congratulate Mach et al. for their report in the July 3 issue on the unequivocal scintigraphic identification of tumor sites in 11 of 27 patients given [131I]-labeled antibody to carcinoembryonic antigen (CEA) — a method that has been described as the radioimmunodetection of cancer.1 This report corrects the authors' previous claim that cancer radioimmunodetection in human beings with radioactive CEA antibodies is not feasible, 2 and we ascribe the earlier failure to their not using the computer-assisted background-subtraction method described in our original clinical study of CEA tumor radioimmunodetection.3 Although their paper confirms our report that.

Original languageEnglish (US)
Pages (from-to)1237-1239
Number of pages3
JournalNew England Journal of Medicine
Volume303
Issue number21
DOIs
StatePublished - Nov 20 1980

ASJC Scopus subject areas

  • Medicine(all)

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