Tumor immunology - Towards a paradigm of reciprocal research

Charles G. Drake; Drew M. Pardoll

doi:10.1006/scbi.2001.0403

Tumor immunology - Towards a paradigm of reciprocal research

Charles G. Drake, Drew M. Pardoll

School of Medicine

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Recent advances in the field of tumor immunology highlight the difficulties involved in generating and maintaining a tumor-specific immune response. The tendency of T cells to be tolerized in vivo, and the tendency of tumors to escape immune recognition represent significant barriers to successful immunotherapy. The results of early clinical trials illustrate these points and underscore the critical importance of an interactive dialog between laboratory and clinical research efforts.

Original language	English (US)
Pages (from-to)	73-80
Number of pages	8
Journal	Seminars in Cancer Biology
Volume	12
Issue number	1
DOIs	https://doi.org/10.1006/scbi.2001.0403
State	Published - Jan 1 2002

Keywords

Cancer
Tolerance
Tumor immunology
Vaccine

ASJC Scopus subject areas

Cancer Research

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10.1006/scbi.2001.0403

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abstract = "Recent advances in the field of tumor immunology highlight the difficulties involved in generating and maintaining a tumor-specific immune response. The tendency of T cells to be tolerized in vivo, and the tendency of tumors to escape immune recognition represent significant barriers to successful immunotherapy. The results of early clinical trials illustrate these points and underscore the critical importance of an interactive dialog between laboratory and clinical research efforts.",

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AB - Recent advances in the field of tumor immunology highlight the difficulties involved in generating and maintaining a tumor-specific immune response. The tendency of T cells to be tolerized in vivo, and the tendency of tumors to escape immune recognition represent significant barriers to successful immunotherapy. The results of early clinical trials illustrate these points and underscore the critical importance of an interactive dialog between laboratory and clinical research efforts.

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KW - Vaccine

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Tumor immunology - Towards a paradigm of reciprocal research

Abstract

Keywords

ASJC Scopus subject areas

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