Tuberculosis incidence after 36 months' isoniazid prophylaxis in HIV-infected adults in Botswana: A posttrial observational analysis

Taraz Samandari, Tefera B. Agizew, Samba Nyirenda, Zegabriel Tedla, Thabisa Sibanda, Barudi Mosimaneotsile, Oaitse I. Motsamai, Nong Shang, Charles E. Rose, James Shepherd

Research output: Contribution to journalArticle

Abstract

Objective: Thirty-six months of isoniazid preventive therapy (36IPT) was superior to 6 months of IPT (6IPT) in preventing tuberculosis (TB) among HIV-infected adults in Botswana. We assessed the posttrial durability of this benefit.

Original languageEnglish (US)
Pages (from-to)351-359
Number of pages9
JournalAIDS
Volume29
Issue number3
DOIs
StatePublished - Feb 1 2015
Externally publishedYes

Keywords

  • Antiretroviral therapy
  • HIV
  • Isoniazid
  • Preventive therapy
  • Tuberculin
  • Tuberculosis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases
  • Medicine(all)

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  • Cite this

    Samandari, T., Agizew, T. B., Nyirenda, S., Tedla, Z., Sibanda, T., Mosimaneotsile, B., Motsamai, O. I., Shang, N., Rose, C. E., & Shepherd, J. (2015). Tuberculosis incidence after 36 months' isoniazid prophylaxis in HIV-infected adults in Botswana: A posttrial observational analysis. AIDS, 29(3), 351-359. https://doi.org/10.1097/QAD.0000000000000535