Tuberculosis incidence after 36 months' isoniazid prophylaxis in HIV-infected adults in Botswana: A posttrial observational analysis

Taraz Samandari; Tefera B. Agizew; Samba Nyirenda; Zegabriel Tedla; Thabisa Sibanda; Barudi Mosimaneotsile; Oaitse I. Motsamai; Nong Shang; Charles E. Rose; James Shepherd

doi:10.1097/QAD.0000000000000535

Tuberculosis incidence after 36 months' isoniazid prophylaxis in HIV-infected adults in Botswana: A posttrial observational analysis

Taraz Samandari, Tefera B. Agizew, Samba Nyirenda, Zegabriel Tedla, Thabisa Sibanda, Barudi Mosimaneotsile, Oaitse I. Motsamai, Nong Shang, Charles E. Rose, James Shepherd

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Objective: Thirty-six months of isoniazid preventive therapy (36IPT) was superior to 6 months of IPT (6IPT) in preventing tuberculosis (TB) among HIV-infected adults in Botswana. We assessed the posttrial durability of this benefit.

Original language	English (US)
Pages (from-to)	351-359
Number of pages	9
Journal	AIDS
Volume	29
Issue number	3
DOIs	https://doi.org/10.1097/QAD.0000000000000535
State	Published - Feb 1 2015
Externally published	Yes

Keywords

Antiretroviral therapy
HIV
Isoniazid
Preventive therapy
Tuberculin
Tuberculosis

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases
General Medicine

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10.1097/QAD.0000000000000535

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title = "Tuberculosis incidence after 36 months' isoniazid prophylaxis in HIV-infected adults in Botswana: A posttrial observational analysis",

abstract = "Objective: Thirty-six months of isoniazid preventive therapy (36IPT) was superior to 6 months of IPT (6IPT) in preventing tuberculosis (TB) among HIV-infected adults in Botswana. We assessed the posttrial durability of this benefit.",

keywords = "Antiretroviral therapy, HIV, Isoniazid, Preventive therapy, Tuberculin, Tuberculosis",

author = "Taraz Samandari and Agizew, {Tefera B.} and Samba Nyirenda and Zegabriel Tedla and Thabisa Sibanda and Barudi Mosimaneotsile and Motsamai, {Oaitse I.} and Nong Shang and Rose, {Charles E.} and James Shepherd",

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doi = "10.1097/QAD.0000000000000535",

language = "English (US)",

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T1 - Tuberculosis incidence after 36 months' isoniazid prophylaxis in HIV-infected adults in Botswana

T2 - A posttrial observational analysis

AU - Samandari, Taraz

AU - Agizew, Tefera B.

AU - Nyirenda, Samba

AU - Tedla, Zegabriel

AU - Sibanda, Thabisa

AU - Mosimaneotsile, Barudi

AU - Motsamai, Oaitse I.

AU - Shang, Nong

AU - Rose, Charles E.

AU - Shepherd, James

PY - 2015/2/1

Y1 - 2015/2/1

N2 - Objective: Thirty-six months of isoniazid preventive therapy (36IPT) was superior to 6 months of IPT (6IPT) in preventing tuberculosis (TB) among HIV-infected adults in Botswana. We assessed the posttrial durability of this benefit.

AB - Objective: Thirty-six months of isoniazid preventive therapy (36IPT) was superior to 6 months of IPT (6IPT) in preventing tuberculosis (TB) among HIV-infected adults in Botswana. We assessed the posttrial durability of this benefit.

KW - Antiretroviral therapy

KW - HIV

KW - Isoniazid

KW - Preventive therapy

KW - Tuberculin

KW - Tuberculosis

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DO - 10.1097/QAD.0000000000000535

M3 - Article

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AN - SCOPUS:84927612872

SN - 0269-9370

VL - 29

SP - 351

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JO - AIDS

JF - AIDS

IS - 3

ER -

Tuberculosis incidence after 36 months' isoniazid prophylaxis in HIV-infected adults in Botswana: A posttrial observational analysis

Abstract

Keywords

ASJC Scopus subject areas

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