Costes de la tuberculosis en España: factores relacionados

Translated title of the contribution: Tuberculosis Costs in Spain and Related Factors

José Antonio Gullón, José María García-García, Manuel Ángel Villanueva, Fernando Álvarez-Navascues, Teresa Rodrigo, Martí Casals, Luis Anibarro, Marta María García-Clemente, María Ángeles Jiménez, Ana Bustamante, Antón Penas, José Antonio Caminero, Joan Caylà, Tuberculosis Research Integrated Program Working Group (PIITB)

Research output: Contribution to journalArticlepeer-review


Objective To analyze the direct and indirect costs of diagnosis and management of tuberculosis (TB) and associated factors. Patients and methods Prospective study of patients diagnosed with TB between September 2014 and September 2015. We calculated direct (hospital stays, visits, diagnostic tests, and treatment) and indirect (sick leave and loss of productivity, contact tracing, and rehabilitation) costs. The following cost-related variables were compared: age, gender, country of origin, hospital stays, diagnostic testing, sensitivity testing, treatment, resistance, directed observed therapy (DOT), and days of sick leave. Proportions were compared using the chi-squared test and significant variables were included in a logistic regression analysis to calculate odds ratio (OR) and corresponding 95% confidence intervals. Results 319 patients were included with a mean age of 56.72±20.79 years. The average cost was €10,262.62±14,961.66, which increased significantly when associated with hospital admission, polymerase chain reaction, sputum smears and cultures, sensitivity testing, chest computed tomography, pleural biopsy, drug treatment longer than nine months, DOT and sick leave. In the multivariate analysis, hospitalization (OR=96.8; CI 29–472), sensitivity testing (OR=4.34; CI 1.71–12.1), chest CT (OR=2.25; CI 1.08–4.77), DOT (OR=20.76; CI 4.11–148) and sick leave (OR=26.9; CI 8.51–122) showed an independent association with cost. Conclusion Tuberculosis gives rise to significant health spending. In order to reduce these costs, more control of transmission, and fewer hospital admissions would be required.

Translated title of the contributionTuberculosis Costs in Spain and Related Factors
Original languageSpanish
Pages (from-to)583-589
Number of pages7
JournalArchivos de Bronconeumologia
Issue number12
StatePublished - Dec 1 2016
Externally publishedYes


  • Cost analysis
  • Hospital income
  • Tuberculosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


Dive into the research topics of 'Tuberculosis Costs in Spain and Related Factors: factores relacionados'. Together they form a unique fingerprint.

Cite this