Tuberculosis and hypertension—a systematic review of the literature

Anneline Borchsenius Seegert, Frauke Rudolf, Christian Wejse, Dinesh Neupane

Research output: Contribution to journalReview article

Abstract

Background Tuberculosis (TB) remains a major health problem in low- and middle-income countries, and in many of these countries, the burden of non-communicable diseases such as hypertension is rising. Knowledge about how these diseases influence each other is limited. Methods A systematic review of the literature was performed to evaluate the evidence for an association between hypertension and TB. Results Three retrospective cohort studies, three case–control studies, eight cross-sectional studies, 12 case series, and 20 case reports exploring the association between hypertension and TB were included in the review. One cohort study found a significantly higher prevalence of hypertension among TB patients compared to controls. Cross-sectional studies reported a prevalence of hypertension in TB patients ranging from 0.7% to 38.3%. No studies were designed to assess whether hypertension is a risk factor for developing active TB. Conclusions Overall, no evidence was found to support an association between TB and hypertension; however, the results of this review must be interpreted with caution due to the lack of properly designed studies.

Original languageEnglish (US)
Pages (from-to)54-61
Number of pages8
JournalInternational Journal of Infectious Diseases
Volume56
DOIs
StatePublished - Mar 1 2017
Externally publishedYes

Fingerprint

Tuberculosis
Hypertension
Cohort Studies
Cross-Sectional Studies
Retrospective Studies
Health

Keywords

  • Hypertension
  • Systematic review
  • Tuberculosis

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Tuberculosis and hypertension—a systematic review of the literature. / Seegert, Anneline Borchsenius; Rudolf, Frauke; Wejse, Christian; Neupane, Dinesh.

In: International Journal of Infectious Diseases, Vol. 56, 01.03.2017, p. 54-61.

Research output: Contribution to journalReview article

Seegert, Anneline Borchsenius ; Rudolf, Frauke ; Wejse, Christian ; Neupane, Dinesh. / Tuberculosis and hypertension—a systematic review of the literature. In: International Journal of Infectious Diseases. 2017 ; Vol. 56. pp. 54-61.
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