TY - JOUR
T1 - Tuberculosis and hypertension—a systematic review of the literature
AU - Seegert, Anneline Borchsenius
AU - Rudolf, Frauke
AU - Wejse, Christian
AU - Neupane, Dinesh
N1 - Publisher Copyright:
© 2016 The Author(s)
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2017/3/1
Y1 - 2017/3/1
N2 - Background Tuberculosis (TB) remains a major health problem in low- and middle-income countries, and in many of these countries, the burden of non-communicable diseases such as hypertension is rising. Knowledge about how these diseases influence each other is limited. Methods A systematic review of the literature was performed to evaluate the evidence for an association between hypertension and TB. Results Three retrospective cohort studies, three case–control studies, eight cross-sectional studies, 12 case series, and 20 case reports exploring the association between hypertension and TB were included in the review. One cohort study found a significantly higher prevalence of hypertension among TB patients compared to controls. Cross-sectional studies reported a prevalence of hypertension in TB patients ranging from 0.7% to 38.3%. No studies were designed to assess whether hypertension is a risk factor for developing active TB. Conclusions Overall, no evidence was found to support an association between TB and hypertension; however, the results of this review must be interpreted with caution due to the lack of properly designed studies.
AB - Background Tuberculosis (TB) remains a major health problem in low- and middle-income countries, and in many of these countries, the burden of non-communicable diseases such as hypertension is rising. Knowledge about how these diseases influence each other is limited. Methods A systematic review of the literature was performed to evaluate the evidence for an association between hypertension and TB. Results Three retrospective cohort studies, three case–control studies, eight cross-sectional studies, 12 case series, and 20 case reports exploring the association between hypertension and TB were included in the review. One cohort study found a significantly higher prevalence of hypertension among TB patients compared to controls. Cross-sectional studies reported a prevalence of hypertension in TB patients ranging from 0.7% to 38.3%. No studies were designed to assess whether hypertension is a risk factor for developing active TB. Conclusions Overall, no evidence was found to support an association between TB and hypertension; however, the results of this review must be interpreted with caution due to the lack of properly designed studies.
KW - Hypertension
KW - Systematic review
KW - Tuberculosis
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U2 - 10.1016/j.ijid.2016.12.016
DO - 10.1016/j.ijid.2016.12.016
M3 - Review article
C2 - 28027993
AN - SCOPUS:85010417208
SN - 1201-9712
VL - 56
SP - 54
EP - 61
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
ER -