Abstract
Human immunodeficiency virus infection has profoundly affected the epidemiology, natural history, and clinical presentation of TB. It has also contributed in part to the recent epidemic of MDR-TB in the US and significantly reduced the sensitivity (but not the specificity) of the tuberculin skin test. Further research is needed to determine the optimal strategy for chemoprophylaxis in HIV-infected individuals, new methods of diagnosing TB infection and disease, and new drugs to control MDR-TB. Most importantly, however, further funding is necessary to improve compliance with therapy and chemoprophylaxis in order to regain control of this ancient scourge.
Original language | English (US) |
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Pages (from-to) | 421-433 |
Number of pages | 13 |
Journal | Annals of allergy |
Volume | 71 |
Issue number | 5 |
State | Published - 1993 |
ASJC Scopus subject areas
- Immunology and Allergy