Tuberculosis active case finding: uptake and diagnostic yield among minibus drivers in urban South Africa

Tonderai Mabuto, Ephraim Zwane, Violet Chihota, Gillian Gresak, Salome Charalambous, Gavin J. Churchyard, Christopher J. Hoffmann

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Tuberculosis (TB) active case finding is a part of TB control in areas of higher TB prevalence. Congested public transportation settings may be areas of increased TB transmission. We evaluated the uptake and diagnostic yield of an active TB screening program among minibus drivers in a large public transportation facility in Johannesburg, South Africa.

METHODS: Over an eight month period, we intensively recruited minibus drivers for TB screening with a goal of 80% uptake among the estimated 2000 drivers. All participants were screened for TB symptoms, offered HIV testing, and had sputum collected for smear microscopy and liquid culture.

RESULTS: 686 drivers were screened for TB, representing an uptake of only 34% of all drivers (43% of the target screening). Ten drivers (1.5%) were culture positive for TB, nine of whom were sputum smear microscopy negative. Factors associated with previously undiagnosed TB included a history of incarceration (odds ratio [OR] 5.5, 95% confidence interval: 1.1, 27.3) and HIV positivity (OR 5.3, 95% confidence interval: 1.1, 26.3).

CONCLUSIONS: We identified undiagnosed pulmonary TB cases among drivers but at a level that may be insufficient to justify systematic case finding in this population considering the poor uptake.

Original languageEnglish (US)
Pages (from-to)242
Number of pages1
JournalBMC Public Health
Volume15
DOIs
StatePublished - 2015

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South Africa
Tuberculosis
Sputum
Microscopy
Odds Ratio
HIV
Public Facilities
Confidence Intervals
Pulmonary Tuberculosis

ASJC Scopus subject areas

  • Medicine(all)

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Tuberculosis active case finding : uptake and diagnostic yield among minibus drivers in urban South Africa. / Mabuto, Tonderai; Zwane, Ephraim; Chihota, Violet; Gresak, Gillian; Charalambous, Salome; Churchyard, Gavin J.; Hoffmann, Christopher J.

In: BMC Public Health, Vol. 15, 2015, p. 242.

Research output: Contribution to journalArticle

Mabuto, Tonderai ; Zwane, Ephraim ; Chihota, Violet ; Gresak, Gillian ; Charalambous, Salome ; Churchyard, Gavin J. ; Hoffmann, Christopher J. / Tuberculosis active case finding : uptake and diagnostic yield among minibus drivers in urban South Africa. In: BMC Public Health. 2015 ; Vol. 15. pp. 242.
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