Tuberculosis active case-finding in a mother-tochild HIV transmission prevention programme in Soweto, South Africa

Jean Nachega; Jennifer Coetzee; Tania Adendorff; Regina Msandiwa; Glenda E. Gray; James A. McIntyre; Richard E. Chaisson

doi:10.1097/00002030-200306130-00018

Tuberculosis active case-finding in a mother-tochild HIV transmission prevention programme in Soweto, South Africa

Jean Nachega, Jennifer Coetzee, Tania Adendorff, Regina Msandiwa, Glenda E. Gray, James A. McIntyre, Richard E. Chaisson

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43 Scopus citations

Abstract

HIV markedly increases the risk of tuberculosis. We implemented active tuberculosis case-finding in a prevention of mother-to-child transmission programme in South Africa. Of 438 tuberculin-tested HIV-infected patients, 49% had a reaction ≥ 5 mm induration, 120 underwent further evaluation for active disease. The prevalence of active tuberculosis was 11%, a high rate of tuberculosis in this population, and underscores the need for tuberculosis active case-finding to prevent mortality and transmission, and preventive therapy for latent tuberculosis infection.

Original language	English (US)
Pages (from-to)	1398-1400
Number of pages	3
Journal	AIDS
Volume	17
Issue number	9
DOIs	https://doi.org/10.1097/00002030-200306130-00018
State	Published - Jun 13 2003

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

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abstract = "HIV markedly increases the risk of tuberculosis. We implemented active tuberculosis case-finding in a prevention of mother-to-child transmission programme in South Africa. Of 438 tuberculin-tested HIV-infected patients, 49% had a reaction ≥ 5 mm induration, 120 underwent further evaluation for active disease. The prevalence of active tuberculosis was 11%, a high rate of tuberculosis in this population, and underscores the need for tuberculosis active case-finding to prevent mortality and transmission, and preventive therapy for latent tuberculosis infection.",

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AU - Nachega, Jean

AU - Coetzee, Jennifer

AU - Adendorff, Tania

AU - Msandiwa, Regina

AU - Gray, Glenda E.

AU - McIntyre, James A.

AU - Chaisson, Richard E.

PY - 2003/6/13

Y1 - 2003/6/13

N2 - HIV markedly increases the risk of tuberculosis. We implemented active tuberculosis case-finding in a prevention of mother-to-child transmission programme in South Africa. Of 438 tuberculin-tested HIV-infected patients, 49% had a reaction ≥ 5 mm induration, 120 underwent further evaluation for active disease. The prevalence of active tuberculosis was 11%, a high rate of tuberculosis in this population, and underscores the need for tuberculosis active case-finding to prevent mortality and transmission, and preventive therapy for latent tuberculosis infection.

AB - HIV markedly increases the risk of tuberculosis. We implemented active tuberculosis case-finding in a prevention of mother-to-child transmission programme in South Africa. Of 438 tuberculin-tested HIV-infected patients, 49% had a reaction ≥ 5 mm induration, 120 underwent further evaluation for active disease. The prevalence of active tuberculosis was 11%, a high rate of tuberculosis in this population, and underscores the need for tuberculosis active case-finding to prevent mortality and transmission, and preventive therapy for latent tuberculosis infection.

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Tuberculosis active case-finding in a mother-tochild HIV transmission prevention programme in Soweto, South Africa

Abstract

ASJC Scopus subject areas

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