Tryptophan synthetase from neurospora: A modification in the reaction scheme

Michael D. Garrick, Harrold Elberfeld, Sigmund R. Suskind

Research output: Contribution to journalArticlepeer-review

Abstract

In addition to indole-3-glycerolphosphate, an unreported reaction product has been detected in incubation mixtures containing tryptophan synthetase from Neurospora, indole, and glyceraldehyde-3-phosphate. This product has been tentatively identified as an indole derivative. Since this compound is not formed in incubation mixtures initially containing only enzyme and indole-3-glycerolphosphate, it was concluded that indole-3-glycerolphosphate synthesis and breakdown are not simply the forward and reverse components of a reversible reaction.

Original languageEnglish (US)
Pages (from-to)491-492
Number of pages2
JournalScience
Volume145
Issue number3631
DOIs
StatePublished - Jan 1 1964

ASJC Scopus subject areas

  • General

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