Five cases of Trypanosoma cruzi meningoencephalitis in HIV-infected patients are reported. All patients presented with mass lesions on head computed tomographic scan, trypanosomes in the cerebrospinal fluid and failure to respond to antitoxoplasmosis therapy. Benznidazole therapy was associated with clinical improvement in 1 patient. Another 4 patients had T cruzi identified in a peripheral smear. T cruzi needs to be considered in the differential diagnosis of HIV-infected patients with central nervous system mass lesions if they have a history of appropriate exposure.
|Original language||English (US)|
|Number of pages||8|
|Journal||Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology|
|State||Published - Apr 1 1999|
- Chagas' disease
ASJC Scopus subject areas
- Immunology and Allergy