True hermaphroditism

G. D. Berkovitz, J. A. Rock, M. D. Urban, C. J. Migeon

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Eleven cases of true hermaphroditism (eight previously reported) are presented. The two most recently observed patients had what is to be considered an appropriate endocrine evaluation. This includes karyotyping, and measurement of 24-hour urinary 17-ketosteroids, gonadotropins, plasma testosterone, dihydrotestosterone, and all their precursors before and following a human chorionic gonadotropin stimulation test, and a sexual skin biopsy for androgen receptor binding and 5α-reductase activity. The differential diagnosis of true hermaphroditism is discussed and an approach to gender assignment is presented.

Original languageEnglish (US)
Pages (from-to)290-297
Number of pages8
JournalJohns Hopkins Medical Journal
Issue number6
StatePublished - Dec 1 1982

ASJC Scopus subject areas

  • Medicine(all)


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