TRP Channel Knockout Mice Lose Their Cool

Man Kyo Chung, Michael J. Caterina

Research output: Contribution to journalShort survey

Abstract

Heat and cold transduction by peripheral sensory neurons is a fundamental step in the avoidance of dangerous thermal extremes. In this issue of Neuron, Dhaka et al. and Colburn et al. report that mice lacking the cold- and menthol-gated ion channel TRPM8 exhibit deficient behavioral responses to cold temperatures.

Original languageEnglish (US)
Pages (from-to)345-347
Number of pages3
JournalNeuron
Volume54
Issue number3
DOIs
StatePublished - May 3 2007

ASJC Scopus subject areas

  • Neuroscience(all)

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