tRNA breakdown products as markers for cancer

John Speer, Charles W. Gehrke, Kenneth C. Kuo, T. Phillip Waalkes, Ernest Borek

Research output: Contribution to journalArticlepeer-review


Seven breakdown products of tRNA were quantitated by high pressure liquid chromatography in urine and were related to the creatinine content. In the urine of 26 of 27 patients with 13 different malignancies, there was an elevation of one or more of these “markers”. The levels of excretion vary approximately with the stage of the disease.

Original languageEnglish (US)
Pages (from-to)2120-2123
Number of pages4
Issue number6
StatePublished - Dec 1979

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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