Trisomy 21 and early brain development

Tarik F. Haydar, Roger H Reeves

Research output: Contribution to journalArticle

Abstract

Trisomy for human chromosome 21 (Hsa21) results in Down syndrome (DS). The finished human genome sequence provides a thorough catalog of the genetic elements whose altered dosage perturbs development and function in DS. However, understanding how small alterations in the steady state transcript levels for

Original languageEnglish (US)
Pages (from-to)81-91
Number of pages11
JournalTrends in Neurosciences
Volume35
Issue number2
DOIs
StatePublished - Feb 2012

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Down Syndrome
Chromosomes, Human, Pair 21
Trisomy
Brain
Human Chromosomes
Human Genome

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Trisomy 21 and early brain development. / Haydar, Tarik F.; Reeves, Roger H.

In: Trends in Neurosciences, Vol. 35, No. 2, 02.2012, p. 81-91.

Research output: Contribution to journalArticle

Haydar, Tarik F. ; Reeves, Roger H. / Trisomy 21 and early brain development. In: Trends in Neurosciences. 2012 ; Vol. 35, No. 2. pp. 81-91.
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