Tricuspid annular plane systolic excursion and right ventricular ejection fraction in pediatric and adolescent patients with tetralogy of Fallot, patients with atrial septal defect, and age-matched normal subjects

Martin Koestenberger, Bert Nagel, William Ravekes, Allen D Everett, Hans Peter Stueger, Bernd Heinzl, Erich Sorantin, Gerhard Cvirn, Andreas Gamillscheg

Research output: Contribution to journalArticle

Abstract

Aims: To determine whether TAPSE is an accurate marker of right ventricular (RV) systolic function in patients with tetralogy of Fallot (TOF) and patients with small atrial septal defect (ASD). The tricuspid annular plane systolic excursion (TAPSE) values were measured and compared with RV ejection fraction (EF). Methods and results: A prospective study was conducted in pediatric and adolescent patients with TOF (n = 110), with isolated small secundum ASD (n = 200), and age-matched patients with normally structured heart. The TAPSE values showed a positive correlation with age in both patients with ASD and normal subjects. No significant difference of TAPSE values was seen in control subjects and age-matched ASD patients. The TAPSE was not decreased compared to normal subjects in eight infant TOF patients before corrective surgery. A reduction of TAPSE values with increasing time interval following corrective surgery was seen. After a mean of 7 years TAPSE values become significantly reduced compared to age-matched controls, being below the lower bound of the -2 SD. Conclusion: In ASD patients the systolic RV function was preserved over the pediatric age group when compared to normal subjects. In contrast, although initially preserved, we found an impaired TAPSE with increasing postoperative period in our TOF patients.

Original languageEnglish (US)
Pages (from-to)67-75
Number of pages9
JournalClinical research in cardiology : official journal of the German Cardiac Society
Volume100
Issue number1
DOIs
StatePublished - Jan 2011

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Tetralogy of Fallot
Atrial Heart Septal Defects
Stroke Volume
Pediatrics
Right Ventricular Function
Patient Rights
Postoperative Period
Age Groups
Prospective Studies

Keywords

  • Pediatric patients
  • Right ventricular systolic function
  • Tetralogy of Fallot
  • Tricuspid annular plane systolic excursion

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Tricuspid annular plane systolic excursion and right ventricular ejection fraction in pediatric and adolescent patients with tetralogy of Fallot, patients with atrial septal defect, and age-matched normal subjects. / Koestenberger, Martin; Nagel, Bert; Ravekes, William; Everett, Allen D; Stueger, Hans Peter; Heinzl, Bernd; Sorantin, Erich; Cvirn, Gerhard; Gamillscheg, Andreas.

In: Clinical research in cardiology : official journal of the German Cardiac Society, Vol. 100, No. 1, 01.2011, p. 67-75.

Research output: Contribution to journalArticle

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AU - Ravekes, William

AU - Everett, Allen D

AU - Stueger, Hans Peter

AU - Heinzl, Bernd

AU - Sorantin, Erich

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