TRICOM: Enhanced vaccines as anticancer therapy

Benjamin Levy; Dennis Panicalli; John Marshall

doi:10.1586/14760584.3.4.397

TRICOM: Enhanced vaccines as anticancer therapy

Benjamin Levy, Dennis Panicalli, John Marshall

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

Abstract

Renewed interest in immune therapies for the treatment of cancer has sparked a number of different immune stimulation approaches. These include antibody based, dendritic cell-based and vaccine-based therapies. The poxvirus-based vaccines incorporating a TRIad of COstimulalary Molecules (TRICOM) will be reviewed here. Through stimulation of cancer-specific T-cell responses, researchers have demonstrated interesting clinical efficacy in addition to the high safety profile in clinical trials.

Original language	English (US)
Pages (from-to)	397-402
Number of pages	6
Journal	Expert review of vaccines
Volume	3
Issue number	4
DOIs	https://doi.org/10.1586/14760584.3.4.397
State	Published - Aug 1 2004
Externally published	Yes

Keywords

Canser
TRICOM
Vaccines

ASJC Scopus subject areas

Immunology
Molecular Medicine
Pharmacology
Drug Discovery

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10.1586/14760584.3.4.397

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AU - Panicalli, Dennis

AU - Marshall, John

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AB - Renewed interest in immune therapies for the treatment of cancer has sparked a number of different immune stimulation approaches. These include antibody based, dendritic cell-based and vaccine-based therapies. The poxvirus-based vaccines incorporating a TRIad of COstimulalary Molecules (TRICOM) will be reviewed here. Through stimulation of cancer-specific T-cell responses, researchers have demonstrated interesting clinical efficacy in addition to the high safety profile in clinical trials.

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KW - Vaccines

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TRICOM: Enhanced vaccines as anticancer therapy

Abstract

Keywords

ASJC Scopus subject areas

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