TRICOM: Enhanced vaccines as anticancer therapy

Benjamin Levy, Dennis Panicalli, John Marshall

Research output: Contribution to journalReview articlepeer-review


Renewed interest in immune therapies for the treatment of cancer has sparked a number of different immune stimulation approaches. These include antibody based, dendritic cell-based and vaccine-based therapies. The poxvirus-based vaccines incorporating a TRIad of COstimulalary Molecules (TRICOM) will be reviewed here. Through stimulation of cancer-specific T-cell responses, researchers have demonstrated interesting clinical efficacy in addition to the high safety profile in clinical trials.

Original languageEnglish (US)
Pages (from-to)397-402
Number of pages6
JournalExpert review of vaccines
Issue number4
StatePublished - Aug 1 2004
Externally publishedYes


  • Canser
  • Vaccines

ASJC Scopus subject areas

  • Immunology
  • Molecular Medicine
  • Pharmacology
  • Drug Discovery


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