Triad of severe abdominal pain, inappropriate antidiuretic hormone secretion, and disseminated varicella-zoster virus infection preceding cutaneous manifestations after hematopoietic stem cell transplantation: Utility of pcr for early recognition and therapy

Rachel Rau, Courtney D. Fitzhugh, Kristin Baird, Karroll J. Cortez, Li Li, Steven H. Fischer, Edward W. Cowen, James E. Balow, Thomas J. Walsh, Jeffrey I. Cohen, Alan S. Wayne

Research output: Contribution to journalArticle

Abstract

A hematopoietic stem cell transplant recipient developed abdominal pain, pneumatosis intestinalis, hepatitis, pancreatitis, and inappropriate antidiuretic hormone secretion. Blood for varicella-zoster virus (VZV) DNA polymerase chain reaction was positive. She was treated with acyclovir and subsequently developed VZV antigen-positive zoster. Detection of VZV DNA in blood may be useful for early diagnosis in immunocompromised hosts who present with zoster without skin lesions.

Original languageEnglish (US)
Pages (from-to)265-268
Number of pages4
JournalPediatric Infectious Disease Journal
Volume27
Issue number3
DOIs
Publication statusPublished - Mar 2008
Externally publishedYes

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Keywords

  • Abdominal pain
  • Hematopoietic stem cell transplantation
  • Immunocompromised host
  • Syndrome of inappropriate diuretic hormone
  • Varicella zoster virus infection

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases
  • Microbiology (medical)

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