TY - JOUR
T1 - Trends of HIV-1 risk reduction among initiates into intravenous drug use 1982-1987
AU - Vlahov, David
AU - Anthony, James C.
AU - Celentano, David
AU - Solomon, Liza
AU - Chowdhury, Nurul
N1 - Funding Information:
This research was supported by National Institute on Drug Abuse Grant DA 04334. Acknowledgment is made to Harriet Grossman and Rose Mary Wright for their assistance with the preparation of this muscript.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1991
Y1 - 1991
N2 - To assess how injection practices may have changed during the course of the AIDS epidemic, active intravenous drug users (IVDUs) recruited from the community were asked to report year of first injection as well as specific details about the first 3 months after initial injection: frequencies of injection, using sterile needles, sharing needles and other equipment. For the analysis, the users were sorted into successive cohorts of initiation (by year of first injection), and tests for trends were completed using Mantel-Haenszel statistics. Among the 421 IVDUs who reported first injection between 1982 and 1987, the use of new sterile needles to self-administer drugs increased (p < 05) along with its corollary behavior (i.e., using equipment one is sure that no one else had used before). Conversely, there was a decrease in the proportion of those who always used equipment previously used by another IVDU (p < 05) and a decrease in the number of needle-sharing partners (p < 01). Over the 6 years, heroin as first drug decreased and cocaine increased (p < 01). Although these data are from a cross-sectional interview study, they suggest a shift toward lower risk practices among new IVDUs between 1982 and 1987. The shift from heroin to cocaine is compatible with other evidence on the cocaine epidemic.
AB - To assess how injection practices may have changed during the course of the AIDS epidemic, active intravenous drug users (IVDUs) recruited from the community were asked to report year of first injection as well as specific details about the first 3 months after initial injection: frequencies of injection, using sterile needles, sharing needles and other equipment. For the analysis, the users were sorted into successive cohorts of initiation (by year of first injection), and tests for trends were completed using Mantel-Haenszel statistics. Among the 421 IVDUs who reported first injection between 1982 and 1987, the use of new sterile needles to self-administer drugs increased (p < 05) along with its corollary behavior (i.e., using equipment one is sure that no one else had used before). Conversely, there was a decrease in the proportion of those who always used equipment previously used by another IVDU (p < 05) and a decrease in the number of needle-sharing partners (p < 01). Over the 6 years, heroin as first drug decreased and cocaine increased (p < 01). Although these data are from a cross-sectional interview study, they suggest a shift toward lower risk practices among new IVDUs between 1982 and 1987. The shift from heroin to cocaine is compatible with other evidence on the cocaine epidemic.
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U2 - 10.3109/00952999108992808
DO - 10.3109/00952999108992808
M3 - Article
C2 - 2038982
AN - SCOPUS:0025905396
SN - 0095-2990
VL - 17
SP - 39
EP - 48
JO - American Journal of Drug and Alcohol Abuse
JF - American Journal of Drug and Alcohol Abuse
IS - 1
ER -