Trends in adult-to-adult living donor liver transplant organ donation: the Johns Hopkins experience.

Marwan S. Abougergi, Rudra Rai, Cynthia K. Cohen, Robert Montgomery, Steven F. Solga

Research output: Contribution to journalArticle

Abstract

Adult-to-adult living donor liver transplantation is an increasingly important option for 17000 patients awaiting liver transplantation in the United States. However, adult-to-adult living donor liver transplantation volumes peaked in 2001 (N = 518), and have gradually fallen in 2002 (N = 362), 2003 (N = 321), and 2004 (N = 323). Recent concerns about donor safety and ethical considerations have made careful analysis of donor availability and selection criteria critically important. We conducted a retrospective review of our active liver transplant recipient registry (N = 251) and compared it to our living donor registry (N = 231), which included all potential living donors before the selection process. Fifteen percent of recipients accounted for the majority (53%) of donor evaluations, whereas 42% of recipients did not have even a single donor evaluation. Recipient diagnosis appears to have a significant impact on donor availability, with donors rarely evaluated for patients with alcoholic cirrhosis. Careful and stringent selection criteria rule out 67% of potential donors.

Original languageEnglish (US)
Pages (from-to)28-32
Number of pages5
JournalProgress in Transplantation
Volume16
Issue number1
StatePublished - Mar 2006

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Tissue and Organ Procurement
Living Donors
Tissue Donors
Transplants
Liver
Liver Transplantation
Donor Selection
Patient Selection
Registries
Alcoholic Liver Cirrhosis
Safety

ASJC Scopus subject areas

  • Transplantation

Cite this

Abougergi, M. S., Rai, R., Cohen, C. K., Montgomery, R., & Solga, S. F. (2006). Trends in adult-to-adult living donor liver transplant organ donation: the Johns Hopkins experience. Progress in Transplantation, 16(1), 28-32.

Trends in adult-to-adult living donor liver transplant organ donation : the Johns Hopkins experience. / Abougergi, Marwan S.; Rai, Rudra; Cohen, Cynthia K.; Montgomery, Robert; Solga, Steven F.

In: Progress in Transplantation, Vol. 16, No. 1, 03.2006, p. 28-32.

Research output: Contribution to journalArticle

Abougergi, MS, Rai, R, Cohen, CK, Montgomery, R & Solga, SF 2006, 'Trends in adult-to-adult living donor liver transplant organ donation: the Johns Hopkins experience.', Progress in Transplantation, vol. 16, no. 1, pp. 28-32.
Abougergi, Marwan S. ; Rai, Rudra ; Cohen, Cynthia K. ; Montgomery, Robert ; Solga, Steven F. / Trends in adult-to-adult living donor liver transplant organ donation : the Johns Hopkins experience. In: Progress in Transplantation. 2006 ; Vol. 16, No. 1. pp. 28-32.
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